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Synonyms

sedative

American  
[sed-uh-tiv] / ˈsɛd ə tɪv /

adjective

  1. tending to calm or soothe.

  2. allaying irritability or excitement; assuaging pain; lowering functional activity.


noun

  1. a sedative drug or agent.

sedative British  
/ ˈsɛdətɪv /

adjective

  1. having a soothing or calming effect

  2. of or relating to sedation

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

noun

  1. med a sedative drug or agent

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
sedative Scientific  
/ sĕdə-tĭv /
  1. A drug having a calming or quieting effect, often given to reduce anxiety or to promote relaxation.


Other Word Forms

  • unsedative adjective

Etymology

Origin of sedative

First recorded in 1375–1425; late Middle English (adjective), from Middle French sédatif, from Medieval Latin sēdātīvus; equivalent to sedate + -ive

Explanation

A sedative is a drug that calms you down. If a patient is freaking out about getting an MRI or minor surgery, the doctor might prescribe a sedative to chill them out. A sedative is anything that makes you sedate — peaceful, calm, tranquil. In medicine this word refers to drugs that relieve anxiety or tranquilizers that pretty much knock you out. But other non-pharmaceutical things can have sedative effects, like a soothing cup of tea or a relaxing glass of wine. The tryptophan in turkey is actually a natural sedative — that's why everyone is sleepy after Thanksgiving dinner!

Keep Reading on Vocabulary.com

Vocabulary lists containing sedative

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

And patients may also be given medications after an episode including a type of antihistamine, but they have sedative effects that can cause more problems, such as falls.

From The Wall Street Journal • Apr. 15, 2026

Emergency-room visits for vertigo commonly result in unnecessary diagnostic tests and sedative medications, potentially worsening patient outcomes.

From The Wall Street Journal • Apr. 15, 2026

Later, when Carolyn developed a sensitivity to a sedative used during her monthly lumbar punctures, her doctors switched to another medicine, and the company again denied payment, Austin said.

From Los Angeles Times • Dec. 6, 2024

Prison officials have said they get the sedative pentobarbital from a compounding pharmacy whose identity is shielded by state law.

From Seattle Times • Mar. 11, 2024

But if they had been alerted to the plan, their anxiety could have counteracted the sedative.

From "Artemis Fowl" by Eoin Colfer