plague
Americannoun
-
an epidemic disease that causes high mortality; pestilence.
-
an infectious, epidemic disease caused by a bacterium, Yersinia pestis, characterized by fever, chills, and prostration, transmitted to humans from rats by means of the bites of fleas.
-
any widespread affliction, calamity, or evil, especially one regarded as a direct punishment by God.
a plague of war and desolation.
-
any cause of trouble, annoyance, or vexation.
Uninvited guests are a plague.
verb (used with object)
-
to trouble, annoy, or torment in any manner.
The question of his future plagues him with doubt.
-
to annoy, bother, or pester.
Ants plagued the picnickers.
-
to smite with a plague, pestilence, death, etc.; scourge.
those whom the gods had plagued.
-
to infect with a plague; cause an epidemic in or among.
diseases that still plague the natives of Ethiopia.
-
to afflict with any evil.
He was plagued by allergies all his life.
noun
-
any widespread and usually highly contagious disease with a high fatality rate
-
an infectious disease of rodents, esp rats, transmitted to man by the bite of the rat flea ( Xenopsylla cheopis )
-
See bubonic plague
-
something that afflicts or harasses
-
informal an annoyance or nuisance
-
a pestilence, affliction, or calamity on a large scale, esp when regarded as sent by God
-
archaic used to express annoyance, disgust, etc
a plague on you
verb
-
to afflict or harass
-
to bring down a plague upon
-
informal to annoy
-
Any of various highly infectious, usually fatal epidemic diseases.
-
An often fatal disease caused by the bacterium Yersinia pestis, transmitted to humans usually by fleas that have bitten infected rats or other rodents.
-
◆ Bubonic plague, the most common type, is characterized by the tender, swollen lymph nodes called buboes, fever, clotting abnormalities of the blood, and tissue necrosis. An epidemic of bubonic plague in fourteenth-century Europe and Asia was known as the Black Death.
Related Words
See bother.
Discover More
The term is also used to refer to widespread outbreaks of many kinds, such as a “plague of locusts.”
Other Word Forms
Etymology
Origin of plague
First recorded in 1350–1400; Middle English plage, from Latin plāga “stripe, wound,” Late Latin: “pestilence”
Explanation
When the homeowner described her ant problem as a plague, the exterminator thought she was being a bit melodramatic. After all, a few bugs aren't exactly a huge calamity. Centuries ago, if you had admitted to a friend that you had the plague, that friend would have hightailed it in the other direction. In the Middle Ages, the plague was a horribly contagious illness that spread like wildfire through Europe, killing millions of people. Thanks to the introduction of better hygiene and antibiotics, plague doesn't describe a killer disease as often these days. Instead, it commonly overstates an annoyance, like an apartment dweller claiming his building is plagued by cockroaches.
Vocabulary lists containing plague
A Long Walk to Water
Looking to grow your vocabulary? Check out this interactive, curated word list from our team of English language specialists at Vocabulary.com – one of over 17,000 lists we've built to help learners worldwide!
The Diary of Anne Frank
Interested in learning more words like this one? Our team at Vocabulary.com has got you covered! You can review flashcards, quiz yourself, practice spelling, and more – and it's all completely free to use!
Unit 1: Telling Details
Want to remember this word for good? Start your learning journey today with our library of interactive, themed word lists built by the experts at Vocabulary.com – we'll help you make the most of your study time!
Example Sentences
Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.
At the height of the Plague of Justinian, affected individuals came from a wide range of communities that were often disconnected from one another.
From Science Daily • Apr. 23, 2026
Appeared in the April 4, 2026, print edition as 'Fundraising Woes Plague Private Equity'.
From The Wall Street Journal • Apr. 3, 2026
Plague is no longer found in the UK and the chance of it occurring in a person returning to the country is "very low", the government says.
From BBC • Jul. 12, 2025
Camus’ The Plague is set in Oran, and with this connection in mind he christens his new series of unflinching depictions of massacre.
From Slate • Jun. 6, 2025
Played this game called The Plague, which I did not participate in, by the way!
From "Auggie & Me" by R. J. Palacio
![]()
Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023
Idioms from The American Heritage® Idioms Dictionary copyright © 2002, 2001, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company.