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amitriptyline

American  
[am-i-trip-tuh-leen, -lahyn, -lin] / ˌæm ɪˈtrɪp təˌlin, -ˌlaɪn, -lɪn /

noun

Pharmacology.
  1. a white crystalline powder, C 20 H 23 N, used to treat depression and enuresis.


amitriptyline British  
/ ˌæmɪˈtrɪptɪˌliːn, -lɪn /

noun

  1. a tricyclic antidepressant drug. Formula: C 20 H 23 N

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of amitriptyline

Perhaps ami(no)- + trypt(ophan) + (meth)yl + -ine 2

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Even though amitriptyline increases weight, heart rate and blood pressure it also helps with pain and struggling to sleep.

From BBC

He stresses that drinking coke doesn't replace his amitriptyline tablets - the daily pain medication he takes to try to prevent migraines - but it does sometimes help him "last until the end of the day".

From BBC

Participants taking amitriptyline reported a bigger improvement in their symptom scores after six months compared with those taking a placebo.

From Science Daily

The researchers randomized the children into three groups that received a placebo, the antidepressant amitriptyline or the antiepileptic medication topiramate.

From Nature

The 500 test patients will be given either amitriptyline or a placebo tablet for six months and their symptoms and mood checked regularly.

From BBC