amitriptyline

[am-i-trip-tuh-leen, -lahyn, -lin]

noun

Pharmacology.

1. a white crystalline powder, C 20 H 23 N, used to treat depression and enuresis.

amitriptyline

/ ˌæmɪˈtrɪptɪˌliːn, -lɪn /

noun

1. a tricyclic antidepressant drug. Formula: C 20 H 23 N

Word History and Origins

Origin of amitriptyline¹

Perhaps ami(no)- + trypt(ophan) + (meth)yl + -ine ²

Word History and Origins

Origin of amitriptyline¹

C20: from _amino + _tryptamine + _methyl + _-ine ²

Example Sentences

Even though amitriptyline increases weight, heart rate and blood pressure it also helps with pain and struggling to sleep.

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He stresses that drinking coke doesn't replace his amitriptyline tablets - the daily pain medication he takes to try to prevent migraines - but it does sometimes help him "last until the end of the day".

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The results, published today in The Lancet, showed that patients taking amitriptyline were almost twice as likely to report an overall improvement in symptoms as those taking a placebo.

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Among the drugs studied - which included Prozac and a cheap antidepressant called amitriptyline - only one, called duloxetine, showed any evidence for pain relief.

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The researchers randomized the children into three groups that received a placebo, the antidepressant amitriptyline or the antiepileptic medication topiramate.

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