• synonyms


[ an-ti-his-tuh-meen, -min ]
/ ˌæn tɪˈhɪs təˌmin, -mɪn /

noun Physiology, Pharmacology.

any of certain compounds or medicines that neutralize or inhibit the effect of histamine in the body, used chiefly in the treatment of allergic disorders and colds.

Nearby words

antihemorrhagic factor, antihero, antiheroic, antiheroine, antihidrotic, antihistamine, antihistamines, antihistaminic, antihormone, antihuman, antihuman globulin

Origin of antihistamine

First recorded in 1930–35; anti- + histamine Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2019

Examples from the Web for antihistamine

  • “He gave me a blue pill, which he said was an antihistamine,” said Chelan.

    Two New Bill Cosby Accusers Come Forward: ‘We Challenge Mr. Cosby to End This Nightmare’|Marlow Stern|December 3, 2014|DAILY BEAST
  • And, Zyrtec, an antihistamine, was the highest grossing nonfood of 2008, coming in at $316 million in sales.

  • Elvis also had the painkillers morphine and Demerol; tranquilizers Placidyl and Valium; and Chlorpheniramine, an antihistamine.

    Elvis's Doctor Speaks|Gerald Posner|August 14, 2009|DAILY BEAST

British Dictionary definitions for antihistamine


/ (ˌæntɪˈhɪstəˌmiːn, -mɪn) /


any drug that neutralizes the effects of histamine, used esp in the treatment of allergies
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Word Origin and History for antihistamine



1933, from anti- + histamine.

Online Etymology Dictionary, © 2010 Douglas Harper

Medicine definitions for antihistamine


[ ăn′tē-hĭstə-mēn′, -mĭn ]


Any of several drugs used to counteract the physiological effects of histamine.
Related formsan′ti•hista•mine′ adj.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.

Science definitions for antihistamine


[ ăn′tē-hĭstə-mēn′ ]

Any of various drugs that relieve cold or allergy symptoms by blocking the action of histamine.
The American Heritage® Science Dictionary Copyright © 2011. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.