[ an-ti-his-tuh-meen, -min ]

nounPhysiology, Pharmacology.
  1. any of certain compounds or medicines that neutralize or inhibit the effect of histamine in the body, used chiefly in the treatment of allergic disorders and colds.

Origin of antihistamine

First recorded in 1930–35; anti- + histamine

Words Nearby antihistamine Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2023

How to use antihistamine in a sentence

British Dictionary definitions for antihistamine


/ (ˌæntɪˈhɪstəˌmiːn, -mɪn) /

  1. any drug that neutralizes the effects of histamine, used esp in the treatment of allergies

Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Scientific definitions for antihistamine


[ ăn′tē-hĭstə-mēn′ ]

  1. Any of various drugs that relieve cold or allergy symptoms by blocking the action of histamine.

The American Heritage® Science Dictionary Copyright © 2011. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.