histamine

American  

[his-tuh-meen, -min] / ˈhɪs təˌmin, -mɪn /

Also histamin

noun

1. Biochemistry, Physiology. a heterocyclic amine, C 5 H 9 N 3 , released by mast cells when tissue is injured or in allergic and inflammatory reactions, causing dilation of small blood vessels and smooth muscle contraction.

2. Pharmacology. a commercial form of this compound, obtained from histidine and used chiefly in the diagnosis of gastric and circulatory functions.

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histamine British  

/ -mɪn, ˈhɪstəˌmiːn, ˌhɪstəˈmɪnɪk /

noun

1. an amine formed from histidine and released by the body tissues in allergic reactions, causing irritation. It also stimulates gastric secretions, dilates blood vessels, and contracts smooth muscle. Formula: C 5 H 9 N 3 See also antihistamine

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histamine Scientific  

/ hĭs′tə-mēn′ /

1. An organic compound found widely in animals and plants that in humans and other mammals is released as part of the body's immune response, causing physiological changes including dilation of the blood vessels, contraction of smooth muscle (as in the airways), and increased gastric acid secretion. The itching and sneezing typical of respiratory allergies are caused by the release of histamine. Chemical formula: C ₅ H ₉ N ₃

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Other Word Forms

• histaminic adjective

Etymology

Origin of histamine

First recorded in 1910–15; hist(idine) + -amine

Example Sentences

For instance, measuring histamines, which are typically detected in urine at concentrations ranging from about 45 to 190 nanomoles, would ordinarily require a 24-hour urine collection and a sophisticated laboratory analysis.

From Science Daily

Oats soothe skin inflammation with a group of compounds called avenanthramides, which block the release of inflammatory compounds and histamines to reduce redness and itching.

From National Geographic

These white blood cells are loaded with small sacs called "granules," which are full of enzymes and signaling molecules like histamine.

From Science Daily

Those intolerant to histamine may grapple with these symptoms because their body is unable to break down and eliminate this compound.

From Salon

Another possible culprit is histamine - an ingredient more common in red wine than white or rose.

From BBC