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histidine

American  
[his-ti-deen, -din] / ˈhɪs tɪˌdin, -dɪn /
Also histidin

noun

Biochemistry.
  1. an essential amino acid, C 3 H 3 N 2 CH 2 CH(NH2 )COOH, that is a constituent of proteins and is important as the iron-binding site in hemoglobin. His; H


histidine British  
/ ˈhɪstɪˌdiːn, -dɪn /

noun

  1. a nonessential amino acid that occurs in most proteins: a precursor of histamine

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

histidine Scientific  
/ hĭs′tĭ-dēn′ /
  1. An amino acid that is essential for children but not for adults. Chemical formula: C 6 H 9 N 3 O 2 .


Etymology

Origin of histidine

First recorded in 1895–1900; hist- + -id 3 + -ine 2

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

When the relative amount of histidine was high, the bees reduced their overall food intake.

From Science Daily ● Aug. 19, 2026

This was not the feared 226L mutation: The amino acid had changed to a histidine instead of leucine.

From Science Magazine ● Dec. 5, 2024

The sequencing data revealed a variant that substituted an amino acid called histidine for arginine.

From Scientific American ● Jul. 26, 2021

And a molecule of histidine contains only so many suitable atoms.

From Economist ● Feb. 23, 2012

Nothing is known, however, of the process by which the more complicated closed-ring amino-acid compounds, such as proline, histidine, or tryptophane, are synthetized.

From The Chemistry of Plant Life by Roscoe Wilfred Thatcher

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