apoptosis

American  

[ap-uh-toh-sis, ap-uhp‑] / ˌæp əˈtoʊ sɪs, ˌæp əp‑ /

noun

1. a normal, genetically regulated process leading to the death of cells and triggered by the presence or absence of certain stimuli, as DNA damage.

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apoptosis British  

/ ˌæpəpˈtəʊsɪs /

noun

1. Also called: programmed cell death.  biology the programmed death of some of an organism's cells as part of its natural growth and development

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apoptosis Scientific  

/ ăp′əp-tō′sĭs,ăp′ə-tō′- /

1. A natural process of self-destruction in certain cells, such as epithelial cells and erythrocytes, that are genetically programmed to have a limited life span or are damaged. Apoptosis can be induced either by a stimulus, such as irradiation or toxic drugs, or by removal of a repressor agent. The cells disintegrate into membrane-bound particles that are then eliminated by phagocytosis.

2. Also called programmed cell death

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apoptosis Cultural  

1. The programmed death of a cell. Scientists believe that this process is governed by chemical signals a given cell receives from its neighbors.

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It is thought some forms of cancer may result when this process of cell death is somehow interrupted, allowing cells to grow unchecked, with the result being a cancerous tumor.

Other Word Forms

• apoptotic adjective

Etymology

Origin of apoptosis

1970–75; New Latin < Greek apόptōsis a falling off, equivalent to apo- apo- ( def. ) + ptōsis ptosis ( def. )

Example Sentences

The findings suggest that dead cancer cells in the treated group were removed through apoptosis, a controlled cell death process, before they could release cfChPs into the surrounding environment.

From Science Daily

Unlike apoptosis, which quietly removes cells, necroptosis produces signals that draw immune cells to the area.

From Science Daily

Possemato says his team has plans to investigate how blocking other cancer cell pathways might trigger apoptosis in response to these chemotherapies.

From Science Daily

"We found that mitochondria provide a kind of decision-making aid: they regulate whether a cell undergoes clean, silent apoptosis or releases pro-inflammatory messenger substances," explains Prof.

From Science Daily

Recent research shows that the infection leads to significant transcriptional modification of genes encoding proteins involved in the mitochondrial network, such as the respiratory chain, apoptosis, and the structural organization of mitochondria.

From Science Daily