asparaginase

American

[uh-spar-uh-juh-neys, -neyz] / əˈspær ə dʒəˌneɪs, -ˌneɪz /

noun

Biochemistry, Pharmacology.

an enzyme that catalyzes the conversion of asparagine to aspartic acid and ammonia, used in the treatment of acute lymphocytic leukemia.

Etymology

Origin of asparaginase

First recorded in 1960–65; asparagine + -ase

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

"When you add asparaginase, you hit mTOR signaling," Yang said.

From Science Daily • Apr. 8, 2024

The largest hurdle was understanding how venetoclax works with asparaginase to stop B-cell leukemia.

From Science Daily • Apr. 8, 2024

"One is an earlier stage that is more resistant to asparaginase and another later stage that is more sensitive to it."

From Science Daily • Apr. 8, 2024

They are produced by the colon bacteria from which asparaginase is extracted.

From Time Magazine Archive

But research physicians treating patients with asparaginase are laboring under grave handicaps.

From Time Magazine Archive

Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023