asparaginase

American

[uh-spar-uh-juh-neys, -neyz] / əˈspær ə dʒəˌneɪs, -ˌneɪz /

noun

Biochemistry, Pharmacology.

an enzyme that catalyzes the conversion of asparagine to aspartic acid and ammonia, used in the treatment of acute lymphocytic leukemia.

Etymology

Origin of asparaginase

First recorded in 1960–65; asparagine + -ase

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

asparaginase

The protein is also downstream of mTOR, the protein targeted by asparaginase.

From Science Daily ● Apr. 8, 2024

"Administering asparaginase alongside venetoclax may lower the risk of ALL relapse, the major reason for treatment failure," said co-author Ching-Hon Pui, MD, St. Jude Department of Oncology Fahad Nassar Al-Rashid Endowed Chair of Leukemia Research.

From Science Daily ● Apr. 8, 2024

"One is an earlier stage that is more resistant to asparaginase and another later stage that is more sensitive to it."

From Science Daily ● Apr. 8, 2024

For another, asparaginase is still forbiddingly expensive, and scarce.

From Time Magazine Archive

So, unfortunately, can certain cancer cells, which explains why asparaginase cannot be effective against all kinds of cancer.

From Time Magazine Archive

Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023