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autoimmune

American  
[aw-toh-i-myoon] / ˌɔ toʊ ɪˈmjun /

adjective

Immunology.
  1. of or relating to the immune response of an organism against any of its own tissues, cells, or cell components.


autoimmune British  
/ ˌɔːtəʊɪˈmjuːn /

adjective

  1. (of a disease) caused by the action of antibodies produced against substances normally present in the body

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms


Etymology

Origin of autoimmune

First recorded in 1950–55; auto- 1 + immune


Explanation

When a condition or illness is described as autoimmune, it means the body's immune system is attacking the body's own cells or tissues. Lupus is one example of an autoimmune disease. Your immune system sends out antibodies to attack bacteria and viruses that shouldn't be in your body. When this system mistakenly attacks substances that are meant to be in your body, it can cause all kinds of problems — this is an autoimmune disorder. Autoimmune is a medical term that's been around since the 1950s, from auto-, "self," and immune, "exempt from a disease."

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Vocabulary lists containing autoimmune

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

At the same time, it suppressed the development of CD4⁺ T cells into Th17 cells, a type of immune cell associated with autoimmune inflammation.

From Science Daily ● Oct. 22, 2026

MS is an autoimmune disease that affects the central nervous system and can result in progressive physical and cognitive decline.

From Los Angeles Times ● Oct. 20, 2026

Doctors then looked into her case further and concluded she in fact did not have the autoimmune disease, which can cause muscle stiffness and problems with walking and talking.

From BBC ● Oct. 20, 2026

Despite the underwhelming data, the approval has given companies more confidence as they go after more ambitious targets in cancer, autoimmune and neurodegenerative spaces.

From The Wall Street Journal ● Oct. 15, 2026

He did find that some people had skin cells that changed color spontaneously, but those were an indication of illness, or conditions like vitiligo, an autoimmune disorder where healthy melanin cells die or stop working.

From "Boy 2.0" by Tracey Baptiste

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