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autoimmune

American  
[aw-toh-i-myoon] / ˌɔ toʊ ɪˈmjun /

adjective

Immunology.
  1. of or relating to the immune response of an organism against any of its own tissues, cells, or cell components.


autoimmune British  
/ ˌɔːtəʊɪˈmjuːn /

adjective

  1. (of a disease) caused by the action of antibodies produced against substances normally present in the body

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

Etymology

Origin of autoimmune

First recorded in 1950–55; auto- 1 + immune

Explanation

When a condition or illness is described as autoimmune, it means the body's immune system is attacking the body's own cells or tissues. Lupus is one example of an autoimmune disease. Your immune system sends out antibodies to attack bacteria and viruses that shouldn't be in your body. When this system mistakenly attacks substances that are meant to be in your body, it can cause all kinds of problems — this is an autoimmune disorder. Autoimmune is a medical term that's been around since the 1950s, from auto-, "self," and immune, "exempt from a disease."

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Vocabulary lists containing autoimmune

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

“I think of it almost like an autoimmune condition. It’s not a classical autoimmune condition, but the body’s definitely attacking itself.”

From The Wall Street Journal Jul. 13, 2026

Its initial focus will be on B-cell-mediated autoimmune diseases like systemic lupus erythematosus—a chronic condition where the immune system attacks healthy tissues and organs.

From Barron's Jun. 26, 2026

Others develop autoimmune gastritis, in which the immune system damages stomach cells involved in producing acid and intrinsic factor, the protein needed for vitamin B12 absorption.

From Science Daily Jun. 25, 2026

In addition to reducing food noise, her primary goal is to lower inflammation in patients with autoimmune conditions.

From Los Angeles Times Jun. 23, 2026

“I don’t know. It just happens to some people. That’s the way autoimmune diseases are.”

From "How to Disappear Completely" by Ali Standish

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