Dictionary.com
Thesaurus.com

autoimmune

American  
[aw-toh-i-myoon] / ˌɔ toʊ ɪˈmjun /

adjective

Immunology.
  1. of or relating to the immune response of an organism against any of its own tissues, cells, or cell components.


autoimmune British  
/ ˌɔːtəʊɪˈmjuːn /

adjective

  1. (of a disease) caused by the action of antibodies produced against substances normally present in the body

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

Etymology

Origin of autoimmune

First recorded in 1950–55; auto- 1 + immune

Explanation

When a condition or illness is described as autoimmune, it means the body's immune system is attacking the body's own cells or tissues. Lupus is one example of an autoimmune disease. Your immune system sends out antibodies to attack bacteria and viruses that shouldn't be in your body. When this system mistakenly attacks substances that are meant to be in your body, it can cause all kinds of problems — this is an autoimmune disorder. Autoimmune is a medical term that's been around since the 1950s, from auto-, "self," and immune, "exempt from a disease."

Keep Reading on Vocabulary.com

Vocabulary lists containing autoimmune

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

As I was recuperating, he was diagnosed with an autoimmune condition, which meant he had to tap out indefinitely.

From Los Angeles Times Sep. 11, 2026

The pelacarsen study results also come less than a week after Novartis said it had paused eight trials of an experimental cell therapy for autoimmune and neurological disorders after three patients died.

From The Wall Street Journal Sep. 7, 2026

She was admitted to hospital four days before her death with kidney and autoimmune issues.

From BBC Sep. 4, 2026

Sami Corwin, who covers biotech for William Blair, was doing a routine check of clinical trials last week when she saw that a slate of studies testing therapies in autoimmune diseases had gone dark.

From The Wall Street Journal Sep. 3, 2026

He did find that some people had skin cells that changed color spontaneously, but those were an indication of illness, or conditions like vitiligo, an autoimmune disorder where healthy melanin cells die or stop working.

From "Boy 2.0" by Tracey Baptiste

Vocabulary.com logo
by dictionary.com

Dictionary.com's Learning Companion

Go beyond just looking up words.
Remember them forever with VocabTrainer.

Start training