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bioavailability

[bahy-oh-uh-vey-luh-bil-i-tee]

noun

Biochemistry.
  1. the extent to which a nutrient or medication can be used by the body.



bioavailability

/ ˌbaɪəʊəˌveɪləˈbɪlɪtɪ /

noun

  1. Also called: systemic availabilitythe extent to which a drug or other substance is taken up by a specific tissue or organ after administration; the proportion of the dose of a drug that reaches the systemic circulation intact after administration by a route other than intravenous

“Collins English Dictionary — Complete & Unabridged” 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
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Other Word Forms

  • bioavailable adjective
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Word History and Origins

Origin of bioavailability1

First recorded in 1965–70; bio- + available ( def. )
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Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

"By contrast, small-molecule drugs that are designed to cross the blood-brain barrier are hydrophobic in nature, which limits their bioavailability, increases the risk of off-target binding, and is linked to side effects."

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Of the many carotenoids found in nature, beta-carotene is the star player: a strong orange tint and high "bioavailability" — the term used to describe drug absorption — make it particularly influential.

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Now that safety and tolerability have been established in healthy adults, the authors said they will be conducting future studies to evaluate the bioavailability and clinical effectiveness of intranasal bumetanide in patients with heart failure.

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Tyrosine has limited bioavailability in living organisms.

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Milk proteins could also potentially affect the absorption, or bioavailability, of caffeine by the human body.

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