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blocker

American  
[blok-er] / ˈblɒk ər /

noun

  1. a person or thing that blocks.

  2. Football. a player whose assignment or special skill is blocking.

  3. Biochemistry. a substance that inhibits the physiological action of another substance, as the beta blocker propranolol that interferes with neurotransmitters in the sympathetic nervous system.


blocker British  
/ ˈblɒkə /

noun

  1. a person or thing that acts as a block

  2. physiol an agent that blocks a physiological function, such as the transport of an ion across an ion channel

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of blocker

Middle English word dating back to 1200–50; see origin at block, -er 1

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Miller is durable and a particularly adept pass blocker.

From Los Angeles Times • Mar. 17, 2026

It might — though there’s a major potential blocker I’ll get to in a moment.

From MarketWatch • Feb. 10, 2026

For those at risk of preterm labor, a PIEZO1 blocker, if developed, could work alongside current medications that relax uterine muscle by limiting calcium entry into cells.

From Science Daily • Jan. 13, 2026

Among some tech leaders it's seen as, at best, a blocker to smoother digital workflows and AI, at worst, an accident waiting to happen.

From BBC • Jan. 8, 2026

He could hit like a locomotive and was a devastating blocker.

From "October Sky" by Homer Hickam

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