cinchonine

American  

[sing-kuh-neen, -nin, sin-] / ˈsɪŋ kəˌnin, -nɪn, ˈsɪn- /

noun

Pharmacology.

1. a colorless, crystalline, slightly water-soluble alkaloid, C 19 H 22 N 2 O, a stereoisomer of cinchonidine, obtained from the bark of various species of cinchona and used chiefly as a quinine substitute.

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cinchonine British  

/ ˈsɪŋkəˌniːn /

noun

1. an insoluble crystalline alkaloid isolated from cinchona bark, used to treat malaria. Formula: C 19 H 22 N 2 O

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Etymology

Origin of cinchonine

First recorded in 1815–25; cinchon(a) + -ine ²

Example Sentences

Cinchonine has the formula C19H22N2O, quinine being methoxy cinchonine, i.e.

From Encyclopaedia Britannica, 11th Edition, Volume 6, Slice 3 "Chitral" to "Cincinnati" by Various

This base was discovered in coal-tar by Runge in 1834, and was obtained by Gerhardt in 1842 by distilling cinchonine, one of the cinchona alkaloïds, with alkali.

From Coal and What We Get from It by Meldola, Raphael

The true cinchona barks, containing quinine, quinidine, and cinchonine, are distinguished from the false by their splintery-fibrous texture, the latter being pre-eminently corky.

From The Andes and the Amazon Across the Continent of South America by Orton, James

It is stated that incomplete examinations have detected cinchonine in the bark.

From Catalogue of Economic Plants in the Collection of the U. S. Department of Agriculture by Saunders, William

Their great value depends upon the presence of certain alkaloid substances called quinine, cinchonine, and quinidine, which exist in the bark in combination with tannic and other acids.

From Catalogue of Economic Plants in the Collection of the U. S. Department of Agriculture by Saunders, William