cinchonine

American  

[sing-kuh-neen, -nin, sin-] / ˈsɪŋ kəˌnin, -nɪn, ˈsɪn- /

noun

Pharmacology.

1. a colorless, crystalline, slightly water-soluble alkaloid, C 19 H 22 N 2 O, a stereoisomer of cinchonidine, obtained from the bark of various species of cinchona and used chiefly as a quinine substitute.

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cinchonine British  

/ ˈsɪŋkəˌniːn /

noun

1. an insoluble crystalline alkaloid isolated from cinchona bark, used to treat malaria. Formula: C 19 H 22 N 2 O

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Etymology

Origin of cinchonine

First recorded in 1815–25; cinchon(a) + -ine ²

Example Sentences

See Examples For:

cinchonine

Quinidine is almost as powerful an antidote to malaria as quinine; cinchonidine has about two-thirds the power of quinine, and cinchonine less than one-half.

From Encyclopaedia Britannica, 11th Edition, Volume 6, Slice 3 "Chitral" to "Cincinnati" by Various

This base was discovered in coal-tar by Runge in 1834, and was obtained by Gerhardt in 1842 by distilling cinchonine, one of the cinchona alkaloïds, with alkali.

From Coal and What We Get from It by Raphael Meldola

The true cinchona barks, containing quinine, quinidine, and cinchonine, are distinguished from the false by their splintery-fibrous texture, the latter being pre-eminently corky.

From The Andes and the Amazon Across the Continent of South America by James Orton

When cinchonine is distilled with solid potassium hydrate, it yields pyrrol and bases of both the pyridine and quinoline series.

From Scientific American Supplement, No. 415, December 15, 1883 by Various

Cinchonine has the formula C19H22N2O, quinine being methoxy cinchonine, i.e.

From Encyclopaedia Britannica, 11th Edition, Volume 6, Slice 3 "Chitral" to "Cincinnati" by Various