cinchonism

American  

[sing-kuh-niz-uhm, sin-] / ˈsɪŋ kəˌnɪz əm, ˈsɪn- /

noun

Pathology.

1. poisoning by any of the cinchona alkaloids, characterized by headache, deafness, and ringing in the ears.

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cinchonism British  

/ ˈsɪŋkəˌnɪzəm /

noun

1. a condition resulting from an excessive dose of cinchona bark or its alkaloids, characterized chiefly by headache, ringing in the ears, and vomiting

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Etymology

Origin of cinchonism

First recorded in 1855–60; cinchon(a) + -ism

Example Sentences

Quinine, a naturally occurring quinoline, and the earliest antimalarial drug, displayed a similar propensity to many of these effects, causing a syndrome known as cinchonism.

From Time • Feb. 13, 2013

Their action, too, is tonic, and, as they rarely produce cinchonism, the objection often made to the use of larger doses does not apply to them.

From A System of Practical Medicine by American Authors, Vol. I Volume 1: Pathology and General Diseases by Various

The amount of quinia necessary to produce cinchonism must be estimated for each particular case according to the measure of its severity or to states of the system more or less favorable to its absorption.

From A System of Practical Medicine by American Authors, Vol. I Volume 1: Pathology and General Diseases by Various

Quinine after or during the operation of the pills, in large doses every two or three hours, until deafness or cinchonism ensued, completed the cure. 

From A Popular Account of Dr. Livingstone's Expedition to the Zambesi and its tributaries And of the Discovery of Lakes Shirwa and Nyassa, 1858-1864 by Livingstone, David

If the period which has elapsed since the beginning of the paroxysm is so considerable that further delay might prevent sufficient cinchonism to intercept the next accession.

From A System of Practical Medicine by American Authors, Vol. I Volume 1: Pathology and General Diseases by Various