colistin

American  

[kuh-lis-tin] / kəˈlɪs tɪn /

noun

Pharmacology.

1. a toxic antibiotic polypeptide, C 45 H 85 O 10 N 13 , produced by the bacterium Bacillus colistinus, used in sulfate form against a broad spectrum of microorganisms and in the treatment of severe gastroenteritis.

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Etymology

Origin of colistin

1950–55; < New Latin colistinus epithet for a variety of Bacillus polymyxa, equivalent to coli- ( coliform ) + -stinus, apparently an arbitrarily chosen suffix; -in ²

Example Sentences

The study examined eight intravenous drugs active against carbapenem-resistant bacteria - ranging from older antibiotics including Colistin to newer ones such as Ceftazidime-avibactam.

From BBC

For example, colistin, one of the few gram-negative-only antibiotics approved for clinical use, can cause C. difficile-associated diarrhea and pseudomembranous colitis, a potentially life-threatening complication.

From Science Daily

County wastewater that were resistant to colistin, a last-resort antibiotic.

From Los Angeles Times

County wastewater samples, researchers detected two pathogens that not only are resistant to colistin but also have genes that should make them resistant to carbapenems, Smith said.

From Los Angeles Times

That includes in Los Angeles, where a resident who died in 2016 was found to have been infected with E. coli bacteria that carried a colistin resistance gene.

From Los Angeles Times