cytokine storm

American  

[sahy-tuh-kahyn stawrm] / ˈsaɪ təˌkaɪn ˈstɔrm /

noun

1. an overreaction of the immune system, in which an excess of cytokines triggers an onslaught of white blood cells that swarm an infected area of the body, resulting in inflammation, possible tissue damage, and in extreme cases, organ failure.

   A cytokine storm in the lungs of a COVID-19 patient can draw hungry white blood cells into the spaces between air sacs, blocking oxygen from reaching the blood, which can prove fatal.

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Etymology

Origin of cytokine storm

First recorded in 1990–95

Example Sentences

See Examples For:

cytokine storm

But in some cases of severe infection, the immune system can overcorrect and send out an excess amount of these proteins, a serious and potentially fatal reaction called a cytokine storm.

From Los Angeles Times ● Jun. 15, 2026

People with traumatic injuries and those taking some cancer immunotherapies can also experience a cytokine storm.

From Science Daily ● Jan. 17, 2024

An elevated release of proteins known as cytokines can result in a cytokine storm, sparking inflammation and damaging key organs such as the heart.

From Washington Times ● Jan. 27, 2023

However, TNF blockers have been unsuccessful in preventing the cytokine storm that can arise from COVID-19 infections and sepsis.

From Salon ● Jan. 1, 2023

In particular, Yang said, more needs to be understood about the massive immune response called a cytokine storm, which often is what kills covid-19 patients.

From Washington Post ● Oct. 31, 2022