cytokine storm

[sahy-tuh-kahyn stawrm]

noun

1. an overreaction of the immune system, in which an excess of cytokines triggers an onslaught of white blood cells that swarm an infected area of the body, resulting in inflammation, possible tissue damage, and in extreme cases, organ failure.

   A cytokine storm in the lungs of a COVID-19 patient can draw hungry white blood cells into the spaces between air sacs, blocking oxygen from reaching the blood, which can prove fatal.

Word History and Origins

Origin of cytokine storm¹

First recorded in 1990–95

Example Sentences

By delineating these SWI/SNF variants, the team has revealed new immune system mechanisms that could be targeted with therapeutics to regulate inflammation associated with conditions like sepsis, cytokine storm, COVID-19, and many more.

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A serious infection or a severe burn can unleash a cytokine storm in the body.

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People with traumatic injuries and those taking some cancer immunotherapies can also experience a cytokine storm.

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The leaking fluid triggers a cytokine storm and can cause a secondary infection.

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This suggests that a so-called 'cytokine storm' -- an extreme immune response that causes collateral damage to the host -- was behind the increased risk of disease.

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