cytokine storm

American  

[sahy-tuh-kahyn stawrm] / ˈsaɪ təˌkaɪn ˈstɔrm /

noun

1. an overreaction of the immune system, in which an excess of cytokines triggers an onslaught of white blood cells that swarm an infected area of the body, resulting in inflammation, possible tissue damage, and in extreme cases, organ failure.

   A cytokine storm in the lungs of a COVID-19 patient can draw hungry white blood cells into the spaces between air sacs, blocking oxygen from reaching the blood, which can prove fatal.

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Etymology

Origin of cytokine storm

First recorded in 1990–95

Example Sentences

People with traumatic injuries and those taking some cancer immunotherapies can also experience a cytokine storm.

From Science Daily • Jan. 17, 2024

An elevated release of proteins known as cytokines can result in a cytokine storm, sparking inflammation and damaging key organs such as the heart.

From Washington Times • Jan. 27, 2023

While cytokines play an essential role in the immune response, excessive and uncontrolled cytokine production can lead to a dangerous cytokine storm associated with sepsis.

From Salon • Jan. 1, 2023

Other scientists have suggested that children’s developing immune systems have lower levels of the proteins that can cause the potentially deadly immune response known as a cytokine storm.

From Washington Post • Sep. 26, 2022

There’s also no evidence to suggest the Pfizer vaccine would cause a cytokine storm, Longley said.

From Seattle Times • Jul. 9, 2021