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dystrophy

American  
[dis-truh-fee] / ˈdɪs trə fi /
Also dystrophia

noun

  1. Medicine/Medical. faulty or inadequate nutrition or development.

  2. Pathology. any of a number of disorders characterized by weakening, degeneration, or abnormal development of muscle.

  3. Ecology. the state of being dystrophic.


dystrophy British  
/ ˈdɪstrəfɪ /

noun

  1. any of various bodily disorders, characterized by wasting of tissues See also muscular dystrophy

  2. ecology a condition of lake water when it is too acidic and poor in oxygen to support life, resulting from excessive humus content

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

Etymology

Origin of dystrophy

From the New Latin word dystrophia, dating back to 1885–90. See dys-, -trophy

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Separately, Novartis on Monday disclosed another Phase 3 failure of an experimental treatment for people with myotonic dystrophy type 1, which came from its $12 billion acquisition of Avidity Biosciences last year.

From MarketWatch ● Sep. 8, 2026

A really wonderful guy, sort of a self-advocate and kind of a grump, total badass activist who has muscular dystrophy and has a tracheotomy.

From Los Angeles Times ● Aug. 6, 2026

The discovery could guide future research into muscular dystrophy treatments while also offering broader clues about cancer biology.

From Science Daily ● Aug. 2, 2026

Still, the main proof point for the Avidity acquisition will be a late-stage study for another drug, del-desiran, in myotonic dystrophy type 1, according to Jefferies.

From The Wall Street Journal ● Jun. 12, 2026

There were tiny babies with club feet, children who had paralyzed limbs from polio, adolescents dying from muscular dystrophy.

From "My Life with the Chimpanzees" by Jane Goodall

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