epigenome

American

[ep-i-jee-nohm] / ˌɛp ɪˈdʒi noʊm /

noun

Genetics. a network of chemical compounds surrounding DNA that modify the genome without altering the DNA sequences and have a role in determining which genes are active in a particular cell.

Etymology

Origin of epigenome

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

"In animals with heart failure, supplementing additional active TGF-β has been shown to be a potential treatment. Correcting the epigenome of hematopoietic stem cells could also be a way to deplete stress memory."

From Science Daily • May 24, 2024

The study, published in the journal Environmental Health Perspectives, demonstrates a link between long-term exposure to DDT and changes in the sperm epigenome.

From Science Daily • Feb. 8, 2024

“We’re taking a comprehensive approach to this study, looking at body composition, the epigenome or biological clock, the microbiome and the brain,” said Christopher Gardner, a nutrition scientist at Stanford University.

From Salon • Jan. 4, 2024

His relationship to the technology of epigenome mapping was not rational.

From Slate • Feb. 25, 2023

In both cases, the Yamanaka factors appear to have restored part of the animals’ epigenome, chemical modifications on DNA and proteins that help regulate gene activity, to a more youthful state.

From Science Magazine • Jan. 12, 2023

Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023