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epigenome

American  
[ep-i-jee-nohm] / ˌɛp ɪˈdʒi noʊm /

noun

  1. Genetics. a network of chemical compounds surrounding DNA that modify the genome without altering the DNA sequences and have a role in determining which genes are active in a particular cell.


Etymology

Origin of epigenome

epi- + genome

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Unlike DNA itself, the epigenome can change over time.

From Science Daily Feb. 11, 2026

The study, published in the journal Environmental Health Perspectives, demonstrates a link between long-term exposure to DDT and changes in the sperm epigenome.

From Science Daily Feb. 8, 2024

“We’re taking a comprehensive approach to this study, looking at body composition, the epigenome or biological clock, the microbiome and the brain,” said Christopher Gardner, a nutrition scientist at Stanford University.

From Salon Jan. 4, 2024

His relationship to the technology of epigenome mapping was not rational.

From Slate Feb. 25, 2023

In both cases, the Yamanaka factors appear to have restored part of the animals’ epigenome, chemical modifications on DNA and proteins that help regulate gene activity, to a more youthful state.

From Science Magazine Jan. 12, 2023

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