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epitope

American  
[ep-i-tohp] / ˈɛp ɪˌtoʊp /

noun

Immunology.
  1. determinant.


epitope British  
/ ˈɛpɪˌtəʊp /

noun

  1. the site on an antigen at which a specific antibody becomes attached

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of epitope

epi- + -tope, from Greek tópos “place”; topo-

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

When a T cell recognizes a certain part of a pathogen's peptide sequence, scientists call that area an "epitope."

From Science Daily

"Previous efforts to target this receptor have been unsuccessful. But now that we've identified this epitope, there could be a therapeutic path forward to target Fas in tumors," Tushir-Singh said.

From Science Daily

The word "epitope" means the substance that the immune system recognizes and protects against.

From Salon

Others, such as epitope tagging, use antibodies to track marked proteins, revealing their location and abundance in cells and providing hints about their function.

From Science Magazine

B cells respond most strongly when each arm attaches to a different epitope.

From Science Magazine