ergotamine

American  

[ur-got-uh-meen, -min] / ɜrˈgɒt əˌmin, -mɪn /

noun

Pharmacology.

1. a crystalline, water-soluble polypeptide, C 33 H 35 N 5 O 5 , obtained from ergot, used to stimulate uterine contractions during labor and in the treatment of migraine.

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ergotamine Scientific  

/ ûr-gŏt′ə-mēn′,-mĭn /

1. A crystalline alkaloid derived from ergot that induces vasoconstriction and is used especially in the treatment of migraine headaches. Chemical formula: C ₃₃ H ₃₅ N ₅ O ₅ .

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Etymology

Origin of ergotamine

First recorded in 1920–25; ergot + -amine

Example Sentences

Yet even refined, synthetic versions of ergotamine can dangerously narrow blood vessels, so doctors and patients welcomed the triptans, which selectively constrict the blood vessels of the brain.

From Science Magazine

V. ALTOUNIAN/SCIENCE Yet even refined, synthetic versions of ergotamine can dangerously narrow blood vessels, so doctors and patients welcomed the triptans, which selectively constrict the blood vessels of the brain.

From Science Magazine

Indeed, they had already had some success with this approach, having succeeded in the isolation and marketing of ergotamine, a leading drug for the treatment of migraine.

From Salon

This gave him a more rational method of producing a substance that is present only in extremely small quantities in ergotamine.

From Scientific American

After Stoll’s isolation of ergotamine, this was a further step in ergot research and proved to be of practical as well as scientific importance.

From Scientific American