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exonuclease

British  
/ ˌɛksəʊˈnjuːklɪˌeɪz /

noun

  1. an enzyme that is capable of detaching the terminal nucleotide from a nucleic acid chain Compare endonuclease

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

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An exonuclease enzyme is used to digest the ends of the DNA and leave complementary single-stranded sequences that readily pair up.

From Nature

In addition, potentially new mechanisms of transformation are suggested, including mutations in the RNA exonuclease DIS3 and other genes involved in protein translation and homeostasis.

From Nature