endonuclease

[ en-doh-noo-klee-eys, -eyz, -nyoo- ]
/ ˌɛn doʊˈnu kliˌeɪs, -ˌeɪz, -ˈnyu- /

noun Biochemistry.

any of a group of enzymes that degrade DNA or RNA molecules by breaking linkages within the polynucleotide chains.

Nearby words

  1. endomyocarditis,
  2. endomyometritis,
  3. endomysium,
  4. endoneuritis,
  5. endoneurium,
  6. endoparasite,
  7. endopeptidase,
  8. endopericarditis,
  9. endoperidium,
  10. endoperimyocarditis

Origin of endonuclease

First recorded in 1960–65; endo- + nuclease

Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2019


British Dictionary definitions for endonuclease

endonuclease

/ (ˌɛndəʊˈnjuːklɪˌeɪz) /

noun

an enzyme that is responsible for scission of a nucleic acid chain, the action of which is not confined to the terminal nucleotideCompare exonuclease
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Medicine definitions for endonuclease

endonuclease

[ ĕn′dō-nōōklē-ās′, -āz′ ]

n.

Any of a group of enzymes that catalyze the hydrolysis of phosphodiester bonds between nucleic acids in a DNA molecule or RNA sequence.

The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.