[en-doh-noo-klee-eys, -eyz, -nyoo-]
- any of a group of enzymes that degrade DNA or RNA molecules by breaking linkages within the polynucleotide chains.
Origin of endonuclease
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018
- an enzyme that is responsible for scission of a nucleic acid chain, the action of which is not confined to the terminal nucleotideCompare exonuclease
- Any of a group of enzymes that catalyze the hydrolysis of phosphodiester bonds between nucleic acids in a DNA molecule or RNA sequence.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.