fibrinogen

American  

[fahy-brin-uh-juhn] / faɪˈbrɪn ə dʒən /

noun

Biochemistry.

1. a globulin occurring in blood and yielding fibrin in blood coagulation.

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fibrinogen British  

/ ˌfaɪbrɪnəʊˈdʒɛnɪk, ˌfaɪbrɪˈnɒdʒənəs, fɪˈbrɪnədʒən /

noun

1. a soluble protein, a globulin, in blood plasma, converted to fibrin by the action of the enzyme thrombin when blood clots

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fibrinogen Scientific  

/ fī-brĭn′ə-jən /

1. A protein in the blood plasma that is essential for the coagulation of blood. It is converted to fibrin by the action of thrombin in the presence of calcium ions.

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Other Word Forms

• fibrinogenic
  adjective

Etymology

Origin of fibrinogen

First recorded in 1870–75; fibrino- + -gen

Compare meaning

How does fibrinogen compare to similar and commonly confused words? Explore the most common comparisons:

• fibrin vs. fibrinogen

Example Sentences

"But when the two complex together, you only need very small amounts of each to cause damage. There's a synergistic effect with Aβ and fibrinogen."

From Science Daily • Oct. 22, 2025

When Aβ attaches to fibrinogen, it produces unusual clots that resist breakdown.

From Science Daily • Oct. 22, 2025

Earlier work from the group showed that Aβ binds to fibrinogen and connected that interaction to the progression of Alzheimer's disease.

From Science Daily • Oct. 22, 2025

These clots often contain misfolded fibrinogen proteins that prevent the clots from breaking down, and this effect can clog blood vessels and block oxygen flow to the brain and other organs.

From Scientific American • Sep. 1, 2023

Serum, for instance, very quickly loses its power of inducing clotting in fibrinogen solutions.

From Encyclopaedia Britannica, 11th Edition, Volume 4, Slice 1 "Bisharin" to "Bohea" by Various