fibrinogen

[fahy-brin-uh-juhn]

noun

Biochemistry.

1. a globulin occurring in blood and yielding fibrin in blood coagulation.

fibrinogen

/ ˌfaɪbrɪnəʊˈdʒɛnɪk, ˌfaɪbrɪˈnɒdʒənəs, fɪˈbrɪnədʒən /

noun

1. a soluble protein, a globulin, in blood plasma, converted to fibrin by the action of the enzyme thrombin when blood clots

fibrinogen

1. A protein in the blood plasma that is essential for the coagulation of blood. It is converted to fibrin by the action of thrombin in the presence of calcium ions.

Other Word Forms

• fibrinogenic adjective

Word History and Origins

Origin of fibrinogen¹

First recorded in 1870–75; fibrino- + -gen

Example Sentences

Chitosan is already used in some hemostats: its positively charged surface is known to strongly attract negatively charged platelets and fibrinogen, the two major components of a blood clot.

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She, along with summer intern Amelia Staats, found that fibrinogen, a protein involved in blood clotting, is a key culprit in signal interference.

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These clots often contain misfolded fibrinogen proteins that prevent the clots from breaking down, and this effect can clog blood vessels and block oxygen flow to the brain and other organs.

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Yet fibrinogen and D-dimer could still predict cognitive deficits even when differences in severity, assessed through a patient’s need for supplemental oxygen and other factors, were taken into account.

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The main protein in the blood which forms blood clots is called fibrinogen.

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