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fibrinogen

American  
[fahy-brin-uh-juhn] / faɪˈbrɪn ə dʒən /

noun

Biochemistry.
  1. a globulin occurring in blood and yielding fibrin in blood coagulation.


fibrinogen British  
/ fɪˈbrɪnədʒən /

noun

  1. a soluble protein, a globulin, in blood plasma, converted to fibrin by the action of the enzyme thrombin when blood clots

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

fibrinogen Scientific  
/ fī-brĭn′ə-jən /
  1. A protein in the blood plasma that is essential for the coagulation of blood. It is converted to fibrin by the action of thrombin in the presence of calcium ions.


Other Word Forms

Etymology

Origin of fibrinogen

First recorded in 1870–75; fibrino- + -gen

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Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

A humanized antibody that blocks the inflammatory region of fibrinogen is currently in phase-1 trials after animal studies showed protection against neuronal loss.

From Science Daily ● Jan. 8, 2026

Earlier work from the group showed that Aβ binds to fibrinogen and connected that interaction to the progression of Alzheimer's disease.

From Science Daily ● Oct. 22, 2025

Their experiments revealed that while Aβ and fibrinogen alone caused little harm, even small amounts of the combined complex led to major problems.

From Science Daily ● Oct. 22, 2025

But elevated fibrinogen seemed to correlate with brain fog whether or not a person previously had COVID, which indicated that cognitive problems caused by other conditions may also involve fibrinogen.

From Scientific American ● Sep. 1, 2023

This liquid contains all the constituents of the plasma except the fibrinogen.

From Physiology and Hygiene for Secondary Schools by Francis M. Walters

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