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fibronectin

American  
[fahy-bruh-nek-tin] / ˌfaɪ brəˈnɛk tɪn /

noun

Cell Biology.
  1. a fibrous protein that binds to collagen, fibrin, and other proteins and also to the cell membranes, functioning as an anchor and connector.


fibronectin Scientific  
/ fī′brə-nĕk′tn /
  1. Any of several glycoproteins that occur especially in plasma and in soft connective tissue. Fibronectins are important for the adhesion of fibrous extracellular tissue matrices and also play roles in cellular adhesion, embryonic cellular differentiation, phagocytosis, and the aggregation of platelets in blood clotting.


Etymology

Origin of fibronectin

1975–80; fibro- + Latin nect ( ere ) to bind, join together ( see connect, nexus) + -in 2


Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

One strategy would be to prevent harmful amounts of fibronectin from accumulating around the brain's blood vessels.

From Science Daily ● Oct. 19, 2026

Analyses of brain tissue and cerebrospinal fluid showed that elevated fibronectin levels were associated with inflammation in astrocytes.

From Science Daily ● Oct. 19, 2026

These results provided experimental evidence that excess fibronectin can directly contribute to blood-brain barrier damage rather than merely appearing alongside it.

From Science Daily ● Oct. 19, 2026

To better recreate the conditions inside an injured joint, the researchers relied on fibronectin fragments, molecules generated as damaged tissue breaks down, instead of using only conventional laboratory methods to trigger inflammation.

From Science Daily ● Jul. 12, 2026

Researchers do not yet understand exactly how this fibronectin variant relates to senescence, but the finding could help scientists better define what makes senescent cells unique.

From Science Daily ● May 15, 2026

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