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Synonyms

gangrene

American  
[gang-green, gang-green] / ˈgæŋ grin, gæŋˈgrin /

noun

  • gangrenes
    plural
  1. necrosis or death of soft tissue due to obstructed circulation, usually followed by decomposition and putrefaction.

  2. moral or spiritual corruption and decadence that pervades an individual or group.

    “This church body has been afflicted with a spiritual gangrene that is poisoning our relationship with the Lord,” the preacher expostulated.

    Synonyms:
    degeneracy, depravity, rot, decay

verb (used with or without object)

  • gangrenes,
    present (3rd person singular)
  • gangrened,
    past participle,  past
  • gangrening
    present participle
  1. to affect or become affected with gangrene.

gangrene British  
/ ˈɡæŋɡriːn /

noun

  1. death and decay of tissue as the result of interrupted blood supply, disease, or injury

  2. moral decay or corruption

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

verb

  1. to become or cause to become affected with gangrene

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
gangrene Scientific  
/ găng′grēn′ /
  1. Death of tissue in a living body, especially in a limb, caused by a bacterial infection resulting from a blockage of the blood supply to the affected tissue.


gangrene Cultural  
  1. The death and decay of body tissue owing to insufficient supply of blood.


Other Word Forms

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Etymology

Origin of gangrene

First recorded in 1535–45; from Middle French gangrene (earlier cancrene ), from Latin gangraena, from Greek gángraina “an eating sore”


Compare meaning

How does gangrene compare to similar and commonly confused words? Explore the most common comparisons:


Explanation

You don't want gangrene, that's for sure. It's the infection that can develop around a wound that kills the tissue, turning it into a terrible stinking sore. In the days before antibiotics even the smallest scratch could lead to gangrene, and doctors would often cut off a finger or even a limb and then seal it with a red hot poker rather than risk the infection spreading. Special surgeons known as sawbones were famed for the speed they could amputate a limb to avoid gangrene setting in. Enough to stop you ever being nostalgic about the good old days.

Keep Reading on Vocabulary.com

Vocabulary lists containing gangrene

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

He was taken to hospital where a surgeon told his parents Prince Charles and Princess Diana had just had baby boy - before breaking the news that Mark had gangrene in his leg.

From BBC ● Aug. 20, 2026

He learned to patch up injured men in below-deck sea cabins, where gangrene turned a wound black and rotten.

From The Wall Street Journal ● Feb. 6, 2026

Nursing employees told the investigators that the 69-year-old man, who had been admitted with gangrene on his feet, was often confused and sometimes tried to pull out his tubes.

From Los Angeles Times ● Mar. 20, 2025

Her lower legs were amputated after she developed gangrene at age 7.

From Seattle Times ● May 15, 2024

His right foot recovered, but on his left foot gangrene had set in in the toes.

From "Shipwreck at the Bottom of the World" by Jennifer Armstrong

Rochefoucault, who has torn the veil from so many foul gangrenes of the human heart, says, we find something not altogether unpleasant to us in the misfortunes of our best friends.

From The Heart of Mid-Lothian, Volume 1 by Sir Walter Scott

For fungous flesh, it promotes discharge, and destroys both gangrenes and carbuncles.

From The Leper in England: with some account of English lazar-houses by Robert Charles Hope

But there come gangrenes in the heart, or perhaps in the pocket.

From Dr. Wortle's School by Anthony Trollope

The swellings of the tonsils are sensible to the eye and touch externally, and have an elastic rather than an œdematous feel, like parts in the vicinity of gangrenes.

From Zoonomia, Vol. II Or, the Laws of Organic Life by Erasmus Darwin

Simple ulcerations and small gangrenes, as well as the troublesome excoriation, when not in the last stage, yielded promptly to this remedy; the good effect being generally visible from the first application.

From North American Medical and Surgical Journal, Vol. 2, No. 3, July, 1826 by Franklin Bache

One man came limping in, unassisted, on a gangrened leg teeming with worms.

From "Kaffir Boy: An Autobiography" by Mark Mathabane

The appendix may be gangrened, wholly or in part.

From Appendicitis by John Henry Tilden

Yass'm, I walked from Buford's, an' 't was awful hard to do, cause my foot is all sore an' gangrened.

From The Long Roll by Mary Johnston

The wounded men who were not gangrened were carefully kept apart from those who were.

From Memories A Record of Personal Experience and Adventure During Four Years of War by Fannie A. Beers

Then in the midst of the discussion the King had a twinge in his gangrened knee, and signed Forstner's release, in order to be rid of this pertinacious princess.

From A German Pompadour Being the Extraordinary History of Wilhelmine van Grävenitz, Landhofmeisterin of Wirtemberg by Hon. Agnes Blanche Marie Hay

It drags upon me like a prisoner's gangrening fetter, and I'm getting tired of it.

From To-morrow? by Victoria Cross

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