glutathione

[gloo-tuh-thahy-ohn]

noun

Biochemistry.

1. a crystalline, water-soluble peptide of glutamic acid, cysteine, and glycine, C 10 H 17 N 3 O 6 S, found in blood and in animal and plant tissues, and important in tissue oxidations and in the activation of some enzymes.

glutathione

/ ˌɡluːtəˈθaɪəʊn, -θaɪˈəʊn /

noun

1. biochem a tripeptide consisting of glutamic acid, cysteine, and glycine: important in biological oxidations and the activation of some enzymes. Formula: C 10 H 17 N 3 O 6 S

glutathione

1. A polypeptide consisting of glycine, cysteine, and glutamic acid that occurs widely in plant and animal tissues. It is important in cellular respiration in both plants and animals, and serves as a cofactor for many enzymes. It is a major protective mechanism against oxidative stress. For example, it protects red blood cells from hydrogen peroxide, a toxic byproduct of certain metabolic reactions.

Word History and Origins

Origin of glutathione¹

First recorded in 1920–25; gluta(mic acid) + thi- + -one

Word History and Origins

Origin of glutathione¹

C20: from _gluta ( _{mic acid} ) + _thi- + _-one

Example Sentences

Other sellers admitted using regulated ingredients such as kojic acid, hydroquinone and a powerful antioxidant, glutathione, which may cause rashes and other side-effects.

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Patients affected by the disease are found to also experience an imbalance of glutathione regulation, which is important for liver detoxification.

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As a result, glutathione supplements have become increasingly popular as an over-the-counter approach to wellness.

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But how glutathione actually enters mitochondria was unknown until 2021, when Birsoy and his team discovered that a transporter protein called SLC25A39 delivers the package.

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"It has two completely independent domains. One domain senses the glutathione, and the other transports it."

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