1. Genetics. a combination of closely linked DNA sequences on one chromosome that are often inherited together: By comparing haplotypes of a mother and father with those of a fetus, scientists can study how new genetic changes arise.

Origin of haplotype

First recorded in 1965–70;haplo- + type
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British Dictionary definitions for haplotype


  1. a set of alleles inherited by an individual from a single parent
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

haplotype in Medicine


  1. The set of alleles that determine different antigens but are closely linked on one chromosome and inherited as a unit, providing a distinctive genetic pattern used in histocompatibility testing.
  2. The antigenic phenotype determined by closely linked genes inherited as a unit from one parent.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.