haplotype

American

[hap-luh-tahyp] / ˈhæp ləˌtaɪp /

noun

Genetics. a combination of closely linked DNA sequences on one chromosome that are often inherited together.

By comparing haplotypes of a mother and father with those of a fetus, scientists can study how new genetic changes arise.

haplotype British

/ ˈhæpləʊˌtaɪp /

noun

a set of alleles inherited by an individual from a single parent

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of haplotype

First recorded in 1965–70; haplo- + type

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

haplotype

The study revealed high-risk EBV haplotype present in about 70% of NPC cases, compared to about 30% of population carriers.

From Science Daily ● Nov. 15, 2024

In the protected area, there was a dominance of a single mtDNA haplotype labeled as S4.

From Science Daily ● Feb. 20, 2024

The advisory report suggests that haplotype matching should be considered “as a precautionary step in donor selection”, but does not recommend it be mandatory.

From Nature ● Nov. 29, 2016

Metadata such as the total depth of the region and the number of reads that support the called haplotype over the reference sequence is also output.

From Nature ● Feb. 2, 2016

For each subset of candidate SNPs we exhaustively generated all possible haplotype sequences by including/excluding the individual SNPs in the subset.

From Nature ● Feb. 2, 2016

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Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023