human leukocyte antigen: any of a complex of genetically determined antigens, occurring on the surface of almost every human cell, by which one person's cells can be distinguished from another's and the histocompatibility and genetic likeness of any two persons can be established: the major histocompatibility antigen of humans.
Origin of HLA
First recorded in 1965–70
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human leukocyte antigen
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.