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hydrocortisone

American  
[hahy-druh-kawr-tuh-zohn, -sohn] / ˌhaɪ drəˈkɔr təˌzoʊn, -ˌsoʊn /

noun

  1. Biochemistry. a steroid hormone, C 21 H 30 O 5 , of the adrenal cortex, active in carbohydrate and protein metabolism.

  2. Also called cortisol. Pharmacology. a powerful anti-inflammatory drug, C 21 H 30 O 5 , used in the treatment of shock, allergies, certain forms of arthritis, and other conditions.


hydrocortisone British  
/ ˌhaɪdrəʊˈkɔːtɪˌzəʊn /

noun

  1. Also called: cortisol. the principal glucocorticoid secreted by the adrenal cortex; 17-hydroxycorticosterone. The synthesized form is used mainly in treating rheumatic, allergic, and inflammatory disorders. Formula: C 21 H 30 O 5

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

hydrocortisone Scientific  
/ hī′drə-kôr′tĭ-sōn′,-zōn′ /
  1. A preparation of the hormone cortisol that is obtained naturally or produced synthetically and is used widely in the treatment of inflammatory conditions and allergies.


Etymology

Origin of hydrocortisone

First recorded in 1950–55; hydro- 2 + cortisone


Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

They range from mild over-the-counter hydrocortisone to more potent versions available only on prescription.

From BBC ● Apr. 10, 2026

Adrenal insufficiency, also known as Addison’s disease, was a fatal condition until hydrocortisone was invented in the 1930s.

From Slate ● Sep. 9, 2025

The new 'Pulsatility' therapy, the culmination of ten years research by the Bristol team, is designed to deliver standard hydrocortisone replacement to patients via a pump which replicates more closely cortisol's natural rhythmic secretion pattern.

From Science Daily ● Oct. 20, 2023

You can use calamine lotion or over-the-counter hydrocortisone cream to reduce or alleviate the itch.

From Los Angeles Times ● May 24, 2023

“We just give them hydrocortisone and some time away from the storm,” said Saif Ali on a recent day, the beds in his emergency room still sandy from the feet of his patients.

From Washington Post ● Aug. 7, 2022

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