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Synonyms

immunize

American  
[im-yuh-nahyz, ih-myoo-nahyz] / ˈɪm jəˌnaɪz, ɪˈmju naɪz /
especially British, immunise

verb (used with object)

  • immunizes,
    present (3rd person singular)
  • immunized,
    past participle,  past
  • immunizing
    present participle
  1. to make immune, or protected from a disease or the like.

    They are organizing a massive health campaign to immunize millions of children.

    George Washington's army immunized its soldiers against smallpox.

  2. to shield, exempt, or protect.

    There is no moral or legal basis for immunizing victorious nations from scrutiny over their actions in a war.

  3. Law. to grant (a witness) exemption from criminal prosecution, legal liability, or punishment on certain conditions.

    In exchange for her testimony, the court agreed to immunize the witness against prosecution for criminal activities committed during the relevant period.


immunize British  
/ ˈɪmjʊˌnaɪz /

verb

  1. to make immune, esp by inoculation

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Usage

What’s the difference between immunize, vaccinate, and inoculate? In the context of medicine, immunize, inoculate, and vaccinate are often used in overlapping ways, and for good reason—they all involve introducing a substance (especially a vaccine) into a person’s body with the goal of preventing them from getting a particular disease. Vaccinate is the most specific of the three terms, because it always involves introducing a vaccine, which usually consists of a small amount of a killed, weakened, or otherwise modified version of a disease (such as a virus or bacterium). While inoculate has other meanings outside the context of medicine, in modern healthcare it’s typically used interchangeably with vaccinate (though it’s used less commonly). Immunize is slightly different—it means to provide immunity from a specific disease. While the goal of vaccinating someone is often to immunize them, not all vaccines provide permanent immunity. Some vaccines provide what amounts to long-term immunity, while others only lead to temporary protection, after which the body “forgets” how to make certain antibodies. In these cases, a booster shot or dose is often required, consisting of a follow-up vaccination to boost or renew the protection gained from the earlier vaccination. Want to learn more? Read the full breakdown of the difference between immunize, vaccinate, and inoculate.

Other Word Forms

Derived Forms

Inflected Forms

Participles

Conjugated Forms

Present

Past

Future

Etymology

Origin of immunize

First recorded in 1890–95; immune + -ize

Explanation

To immunize someone is to give them a vaccine that protects them against disease. A child's pediatrician can immunize her against measles, polio, and mumps, among many other illnesses. Vaccines work by arming your immune system against being infected — in other words, they produce immunity, or immunize you. In some cases, being exposed to a disease can also immunize you; if you've had chicken pox, you are most likely immune to it and won't get it again. There is also a legal meaning of immunize, "To make legally immune," or "to protect from being prosecuted in court." The Latin root, immunis, means "exempt" or "free."

Keep Reading on Vocabulary.com

Vocabulary lists containing immunize

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Per the researchers’ formula, therefore, holding this ETF for between 10 and 11 years should immunize it from interest rate hikes.

From MarketWatch May 22, 2026

After Epstein’s death, the men used their executor roles—controlling both victims’ compensation and access to records—to try to immunize themselves from personal lawsuits, according to court filings.

From The Wall Street Journal Nov. 23, 2025

But RSV, the leading cause of infant hospitalization nationwide, presents particular risk for the youngest babies, a major reason health experts recommend pregnant women either get vaccinated near their delivery date or immunize their newborns.

From Los Angeles Times Oct. 30, 2025

Stepping above means spending more on finer tailoring and materials, but wealth doesn’t necessarily immunize people from the otherworldly allure of chunky jewelry.

From Salon Jun. 7, 2025

“The embryos still have gills. We immunize the fish against the future man’s diseases.”

From "Brave New World" by Aldous Huxley

For a seller, “fully disclosing essentially immunizes you from liability later.”

From Seattle Times Nov. 30, 2023

Tech companies argue they are protected by Section 230 of the Communications Decency Act, which in general immunizes them from liability for content someone else has posted.

From Washington Times Feb. 17, 2023

If Omicron safely immunizes people and similarly recombines with and tames more pathogenic SARS-CoV-2 variant, that would be “a best-case scenario,” she says.

From Science Magazine Feb. 4, 2022

In court documents, Spring Arbor contends the covid emergency law immunizes it from responsibility for Garrett’s death, even though it was a violent attack that killed him, not the coronavirus.

From Washington Post Aug. 20, 2021

In some we observe that the carrier results from a low-level, incomplete infection with the disease which immunizes him but does not kill the bugs.

From Highways in Hiding by George Oliver Smith

People who aren’t immunized are at a higher risk to contract measles and should monitor their symptoms, officials said.

From Los Angeles Times Jul. 23, 2026

Norway, by contrast, after the discovery of North Sea oil in the 1970s, set up a sovereign-wealth fund through a trust structure independent of central government and thus immunized against political manipulation.

From MarketWatch Jul. 6, 2026

Those who are not immunized or are unsure of their status should monitor themselves closely for signs of infection.

From Los Angeles Times Feb. 19, 2026

The U.S. recommends youngsters to get immunized against 18 diseases, while Denmark recommends 10.

From The Wall Street Journal Dec. 19, 2025

Ultimately, I believe that the similarities between these systems of control overwhelm the differences and that mass incarceration, like its predecessors, has been largely immunized from legal challenge.

From "The New Jim Crow" by Michelle Alexander

Public-health experts have warned against delaying the vaccine or only immunizing the babies of infected women at birth.

From The Wall Street Journal Dec. 5, 2025

And these viral genes may protect us against other viral infections in some cases, or provide antiviral resistance, immunizing rare individuals against HIV for example.

From Salon Jun. 1, 2025

The CDC also recommends the Abrysvo vaccine for pregnant people and immunizing babies against RSV with an antibody known as nirsevimab, also known by the trademarked name Beyfortus.

From Los Angeles Times Dec. 16, 2023

The contracts specify that the vaccines can only be used for immunizing humans and violations in theory could create liability issues for the companies.

From Science Magazine May 30, 2023

She is given a list of pediatricians, and coundess brochures on breast-feeding, and bonding, and immunizing, and samples of baby shampoos and Q-Tips and creams.

From "The Namesake" by Jhumpa Lahiri

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