immunocompromised

American  

[im-yuh-noh-kom-pruh-mahyzd] / ˌɪm yə noʊˈkɒm prə maɪzd /

immune-compromised,

adjective

1. having a compromised or impaired immune response; immunodeficient.

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immunocompromised British  

/ ˌɪmjʊnəʊˈkɒmprəmaɪzd /

adjective

1. having an impaired immune system and therefore incapable of an effective immune response, usually as a result of disease, such as AIDS, that damages the immune system

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Etymology

Origin of immunocompromised

First recorded in 1970–75; immuno- + compromised

Example Sentences

For people like your husband who may be immunocompromised and anxious, these delays can make everything appear worse.

From MarketWatch • May 1, 2026

Anyone can contract human metapneumovirus, but those who are immunocompromised or have other underlying medical conditions are at particular risk of developing severe disease — including pneumonia.

From Los Angeles Times • Mar. 4, 2026

Doctors and researchers agree that one dose is fine in adolescents, but two to three doses are still recommended in older and immunocompromised populations.

From Salon • Feb. 22, 2026

Also, those who are vaccinated but later become immunocompromised may have reduced immunity.

From Slate • Feb. 17, 2026

Wasn’t the mom with cancer supposed to be home, in isolation, immunocompromised?

From "Not Nothing" by Gayle Forman