immunocompromised

American  

[im-yuh-noh-kom-pruh-mahyzd] / ˌɪm jə noʊˈkɒm prə maɪzd /

immune-compromised,

adjective

1. having a compromised or impaired immune response; immunodeficient.

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immunocompromised British  

/ ˌɪmjʊnəʊˈkɒmprəmaɪzd /

adjective

1. having an impaired immune system and therefore incapable of an effective immune response, usually as a result of disease, such as AIDS, that damages the immune system

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Etymology

Origin of immunocompromised

First recorded in 1970–75; immuno- + compromised

Example Sentences

Legionnaires' is caused by bacteria that grow in warm water, leading to flu-like symptoms that can sometimes be fatal without treatment and for those who are immunocompromised.

From BBC • Jul. 10, 2026

For people like your husband who may be immunocompromised and anxious, these delays can make everything appear worse.

From MarketWatch • May 1, 2026

Falling vaccination rates leave immunocompromised individuals especially exposed.

From Salon • Apr. 22, 2026

However, the product is available outside clinical trials through the FDA’s expanded access pathway—often referred to as “compassionate use,” and tailored to patients with immunocompromised conditions or severe disease.

From Barron's • Mar. 17, 2026

Wasn’t the mom with cancer supposed to be home, in isolation, immunocompromised?

From "Not Nothing" by Gayle Forman