immunocompromised

American  

[im-yuh-noh-kom-pruh-mahyzd] / ˌɪm yə noʊˈkɒm prə maɪzd /

immune-compromised,

adjective

1. having a compromised or impaired immune response; immunodeficient.

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immunocompromised British  

/ ˌɪmjʊnəʊˈkɒmprəmaɪzd /

adjective

1. having an impaired immune system and therefore incapable of an effective immune response, usually as a result of disease, such as AIDS, that damages the immune system

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Etymology

Origin of immunocompromised

First recorded in 1970–75; immuno- + compromised

Example Sentences

However, the product is available outside clinical trials through the FDA’s expanded access pathway—often referred to as “compassionate use,” and tailored to patients with immunocompromised conditions or severe disease.

From Barron's • Mar. 17, 2026

Doctors and researchers agree that one dose is fine in adolescents, but two to three doses are still recommended in older and immunocompromised populations.

From Salon • Feb. 22, 2026

There are many people who cannot get vaccinated, including infants and severely immunocompromised populations.

From Slate • Feb. 17, 2026

Rob Davis notes the severity of the current flu season, as well as a population of 85 million people who are high risk or immunocompromised and 25 million people over 65.

From The Wall Street Journal • Jan. 13, 2026

Wasn’t the mom with cancer supposed to be home, in isolation, immunocompromised?

From "Not Nothing" by Gayle Forman