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immunocompromised

American  
[im-yuh-noh-kom-pruh-mahyzd] / ˌɪm jə noʊˈkɒm prə maɪzd /
immune-compromised,

adjective

  1. having a compromised or impaired immune response; immunodeficient.


immunocompromised British  
/ ˌɪmjʊnəʊˈkɒmprəmaɪzd /

adjective

  1. having an impaired immune system and therefore incapable of an effective immune response, usually as a result of disease, such as AIDS, that damages the immune system

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of immunocompromised

First recorded in 1970–75; immuno- + compromised


Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Shkreli came to prominence a decade ago for buying the rights to Daraprim, a drug used to treat a rare parasitic infection known as toxoplasmosis that primarily affects people who are immunocompromised.

From MarketWatch ● Oct. 13, 2026

Eighty-five percent of kindergarten-age students in Lancaster County, where the recent deaths occurred, are vaccinated against measles - well below the 95% rate needed for herd immunity to limit the spread and protect immunocompromised people.

From BBC ● Aug. 25, 2026

Doctors and insurers face uncertainty over whether mFlusiva will be recommended only for specific people such as those who are immunocompromised.

From The Wall Street Journal ● Aug. 6, 2026

Anyone can contract human metapneumovirus, but those who are immunocompromised or have other underlying medical conditions are at particular risk of developing severe disease — including pneumonia.

From Los Angeles Times ● Mar. 4, 2026

Wasn’t the mom with cancer supposed to be home, in isolation, immunocompromised?

From "Not Nothing" by Gayle Forman

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