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Synonyms

inactivate

American  
[in-ak-tuh-veyt] / ɪnˈæk təˌveɪt /

verb (used with object)

inactivated, inactivating
  1. to make inactive.

    The bomb was inactivated.

  2. Immunology. to stop the activity of (certain biological substances).


inactivate British  
/ ɪnˈæktɪˌveɪt /

verb

  1. (tr) to render inactive

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

Etymology

Origin of inactivate

First recorded in 1905–10; inactive + -ate 1

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Some batches did not fully inactivate the virus, and in 1955 the vaccine resulted in 10 deaths and 200 vaccine-related cases of polio paralysis.

From The Wall Street Journal Jun. 21, 2026

Pasteurization and proper cooking techniques inactivate the virus.

From Los Angeles Times Dec. 24, 2024

In addition to the mice studies, the researchers also tested to determine which temperatures and time intervals inactivate H5N1 virus in raw milk from dairy cows.

From Science Daily May 24, 2024

Research so far has shown that virus particles end up in the milk of infected cows, but that pasteurization will inactivate the virus.

From Salon May 20, 2024

Extracts in which no attempt was made to inactivate the enzymes present proved unsatisfactory.

From Myology and Serology of the Avian Family Fringillidae A Taxonomic Study by Stallcup, William B.

That means someone inherits two copies of an inactivated gene.

From The Wall Street Journal Mar. 12, 2026

Use of gene therapies becomes more challenging as patients age and grow, because treating them often requires higher doses of the inactivated viruses used to deliver the replacement genes.

From Barron's Nov. 25, 2025

In flu, the inactivated flu injection that is given to adults is updated every year - as is the live vaccine that is given to children as a nasal spray.

From BBC Aug. 6, 2025

If you consume pasteurized milk products and thoroughly cook your chicken and eggs, there is nothing to worry about as bird flu is inactivated by heat.

From Salon Jun. 5, 2024

If a mutation inactivated even one function, the mold would be unable to grow—unless the missing ingredient was supplied back into the broth.

From "The Gene" by Siddhartha Mukherjee

The ubiquitination of cGAS also marks it for destruction, effectively inactivating the sentinel once the threat of an invader has been neutralized.

From Science Daily Feb. 28, 2024

Phosphorylation adds a phosphate group to serine, threonine, and tyrosine residues in a protein, changing their shapes, and activating or inactivating the protein.

From Textbooks Jun. 9, 2022

Finally, there is air disinfection: inactivating viruses using ultraviolet light.

From Scientific American Jun. 8, 2022

Cancer geneticist Alberto Bardelli of the University of Turino and colleagues went further by deliberately inactivating a mismatch repair gene in tumor-bearing mice.

From Science Magazine Apr. 19, 2022

Ultraviolet germicidal irradiation, the placement of UV-C lamps in the air ducts or above dropped ceilings, is extremely effective at inactivating the coronavirus and influenza viruses and even tuberculosis bacteria.

From Washington Post Apr. 3, 2022

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