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Synonyms

inactivate

American  
[in-ak-tuh-vayt] / ɪnˈæk təˌveɪt /

verb (used with object)

inactivated, inactivating
  1. to make inactive.

    The bomb was inactivated.

  2. Immunology. to stop the activity of (certain biological substances).


inactivate British  
/ ɪnˈæktɪˌveɪt /

verb

  1. (tr) to render inactive

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

Etymology

Origin of inactivate

First recorded in 1905–10; inactive + -ate 1

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Meanwhile, Salk’s injectable vaccine, which used formalin to inactivate the virus, was approved in 1955.

From The Wall Street Journal ● Jun. 21, 2026

Pasteurization and proper cooking techniques inactivate the virus.

From Los Angeles Times ● Dec. 24, 2024

However, wood's ability to inactivate viruses has yet to be explored, which is what Varpu Marjomäki and colleagues set out to study.

From Science Daily ● Jun. 19, 2024

Research so far has shown that virus particles end up in the milk of infected cows, but that pasteurization will inactivate the virus.

From Salon ● May 20, 2024

Extracts in which no attempt was made to inactivate the enzymes present proved unsatisfactory.

From Myology and Serology of the Avian Family Fringillidae A Taxonomic Study by William B. Stallcup

"We discovered that, in conditions of high blood pressure, the lateral parafacial region is activated and, when our team inactivated this region, blood pressure fell to normal levels."

From Science Daily ● Mar. 22, 2026

That means someone inherits two copies of an inactivated gene.

From The Wall Street Journal ● Mar. 12, 2026

Use of gene therapies becomes more challenging as patients age and grow, because treating them often requires higher doses of the inactivated viruses used to deliver the replacement genes.

From Barron's ● Nov. 25, 2025

The other main form of polio vaccine is given by injection and contains inactivated polio virus.

From BBC ● Aug. 30, 2024

If a mutation inactivated even one function, the mold would be unable to grow—unless the missing ingredient was supplied back into the broth.

From "The Gene" by Siddhartha Mukherjee

The results highlight acidity as a key factor in inactivating the pathogen during cheesemaking.

From Science Daily ● Oct. 21, 2025

The vaccine, which cost pennies per dose, was made like the human one, by growing the virus in eggs and then inactivating it with chemicals.

From Science Magazine ● Apr. 6, 2023

Phosphorylation adds a phosphate group to serine, threonine, and tyrosine residues in a protein, changing their shapes, and activating or inactivating the protein.

From Textbooks ● Jun. 9, 2022

Ultraviolet germicidal irradiation, the placement of UV-C lamps in the air ducts or above dropped ceilings, is extremely effective at inactivating the coronavirus and influenza viruses and even tuberculosis bacteria.

From Washington Post ● Apr. 3, 2022

Now the newer study contends that inactivating the virus in the mouth’s saliva and mucous membranes could help reduce infection in the adjoining nasopharyngeal area, too.

From Scientific American ● Feb. 24, 2022

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