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Synonyms

inactivate

American  
[in-ak-tuh-veyt] / ɪnˈæk təˌveɪt /

verb (used with object)

inactivated, inactivating
  1. to make inactive.

    The bomb was inactivated.

  2. Immunology. to stop the activity of (certain biological substances).


inactivate British  
/ ɪnˈæktɪˌveɪt /

verb

  1. (tr) to render inactive

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

Etymology

Origin of inactivate

First recorded in 1905–10; inactive + -ate 1

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Some batches did not fully inactivate the virus, and in 1955 the vaccine resulted in 10 deaths and 200 vaccine-related cases of polio paralysis.

From The Wall Street Journal Jun. 21, 2026

“I also want to just stress that there’s nothing, there’s no cooking of the mushroom or freezing of the mushroom that would inactivate the toxin,” Smollin said.

From Los Angeles Times Jan. 16, 2026

By engineering the mouse embryo to kill or inactivate its own olfactory neurons, the researchers could easily determine if rat neurons had restored the animals' sense of smell.

From Science Daily Apr. 25, 2024

Pasteurization should also inactivate flu viruses, which are known to be fragile and heat-sensitive, experts said.

From New York Times Apr. 23, 2024

Extracts in which no attempt was made to inactivate the enzymes present proved unsatisfactory.

From Myology and Serology of the Avian Family Fringillidae A Taxonomic Study by William B. Stallcup

One is normal and functional, while the other has been inactivated by cellular metabolism.

From Science Daily Aug. 17, 2026

That means someone inherits two copies of an inactivated gene.

From The Wall Street Journal Mar. 12, 2026

Use of gene therapies becomes more challenging as patients age and grow, because treating them often requires higher doses of the inactivated viruses used to deliver the replacement genes.

From Barron's Nov. 25, 2025

With such vaccines, called whole-virus vaccines, a person’s immune system is presented with the whole virus, often in weakened or inactivated form.

From Salon Sep. 5, 2025

If a mutation inactivated even one function, the mold would be unable to grow—unless the missing ingredient was supplied back into the broth.

From "The Gene" by Siddhartha Mukherjee

The results highlight acidity as a key factor in inactivating the pathogen during cheesemaking.

From Science Daily Oct. 21, 2025

The vaccine, which cost pennies per dose, was made like the human one, by growing the virus in eggs and then inactivating it with chemicals.

From Science Magazine Apr. 6, 2023

Phosphorylation adds a phosphate group to serine, threonine, and tyrosine residues in a protein, changing their shapes, and activating or inactivating the protein.

From Textbooks Jun. 9, 2022

Ultraviolet germicidal irradiation, the placement of UV-C lamps in the air ducts or above dropped ceilings, is extremely effective at inactivating the coronavirus and influenza viruses and even tuberculosis bacteria.

From Washington Post Apr. 3, 2022

Now the newer study contends that inactivating the virus in the mouth’s saliva and mucous membranes could help reduce infection in the adjoining nasopharyngeal area, too.

From Scientific American Feb. 24, 2022

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