[ verb in-vaj-uh-neyt; adjective in-vaj-uh-nit, -neyt ]
/ verb ɪnˈvædʒ əˌneɪt; adjective ɪnˈvædʒ ə nɪt, -ˌneɪt /

verb (used with object), in·vag·i·nat·ed, in·vag·i·nat·ing.

to insert or receive, as into a sheath; sheathe.
to fold or draw (a tubular organ) back within itself; intussuscept.

verb (used without object), in·vag·i·nat·ed, in·vag·i·nat·ing.

to become invaginated; undergo invagination.
to form a pocket by turning in.


folded or turned back upon itself.

Origin of invaginate

1650–60; < Medieval Latin invāgīnātus, past participle of invāgīnāre to sheathe. See in-2, vaginate

Related forms

un·in·vag·i·nat·ed, adjective Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2019

British Dictionary definitions for invaginate


verb (ɪnˈvædʒɪˌneɪt)

pathol to push one section of (a tubular organ or part) back into itself so that it becomes ensheathed; intussuscept
(intr) (of the outer layer of an organism or part) to undergo invagination

adjective (ɪnˈvædʒɪnɪt, -ˌneɪt)

(of an organ or part) folded back upon itself

Derived Forms

invaginable, adjective

Word Origin for invaginate

C19: from Medieval Latin invāgīnāre, from Latin in- ² + vāgīna sheath
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Medicine definitions for invaginate


[ ĭn-văjə-nāt′ ]


To infold or become infolded so as to form a hollow space within a previously solid structure, as in the formation of a gastrula from a blastula.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.