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Synonyms

isolate

American  
[ahy-suh-layt, ahy-suh-lit, -layt] / ˈaɪ səˌleɪt, ˈaɪ sə lɪt, -ˌleɪt /

verb (used with object)

  • isolates,
    present (3rd person singular)
  • isolated,
    past participle,  past
  • isolating
    present participle
  1. to set or place apart; detach or separate so as to be alone.

  2. Medicine/Medical. to keep (an infected person) from contact with noninfected persons; quarantine.

  3. Chemistry, Bacteriology. to obtain (a substance or microorganism) in an uncombined or pure state.

  4. Electricity. to insulate.

  5. Television. to single out (a person, action, etc.) for a camera closeup.


noun

  1. a person, thing, or group that is set apart or isolated, as for purposes of study.

  2. Psychology. a person, often shy or lacking in social skills, who avoids the company of others and has no friends within a group.

  3. Biology. an inbreeding population that is isolated from similar populations by physiological, behavioral, or geographic barriers.

  4. Also called language isolate. Linguistics. a language with no demonstrable genetic relationship, as Basque.

  5. something that has been isolated, as a by-product in a manufacturing process.

    an isolate of soy flour.

adjective

  1. isolated; alone.

isolate British  

verb

  1. to place apart; cause to be alone

  2. med to quarantine (a person or animal) having or suspected of having a contagious disease

  3. to obtain (a compound) in an uncombined form

  4. to obtain pure cultures of (bacteria, esp those causing a particular disease)

  5. electronics to prevent interaction between (circuits, components, etc); insulate

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

noun

  1. an isolated person or group

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

Derived Forms

Inflected Forms

Participles

Conjugated Forms

Present

Past

Future


Etymology

Origin of isolate

First recorded in 1800–10; back formation from isolated


Explanation

When you remove or set apart one thing from others, you isolate it. You could isolate yourself from people by living in a remote hut or, if you're a biologist, you could isolate a chromosome. The verb isolate comes from the adjective isolated, which comes from the Latin insulatas, meaning “made into an island.” You may have heard the John Donne quote, “No man is an island.” Donne was claiming that no matter how much you might try to isolate yourself from the rest of humanity, in the end people are all connected to one another. Humanity’s need for connectedness may, in fact, be illustrated by the fact that jailers frequently isolate criminals as punishment.

Keep Reading on Vocabulary.com

Vocabulary lists containing isolate

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

"The colleagues from Hanover and I used various methods to isolate the particles from Ukrainian soil samples and attach them to tungsten electrodes," Weissenborn explains.

From Science Daily ● Oct. 23, 2026

Aggregate figures cannot isolate Maia’s contribution, so management’s explanation of infrastructure costs and product mix will matter.

From MarketWatch ● Oct. 16, 2026

Rights group Amnesty International urged countries to "resist" the move, saying the sanctions were "designed to isolate and ultimately destroy" the court.

From Barron's ● Oct. 9, 2026

We could isolate someone and keep everyone else uninfected.

From The Wall Street Journal ● Oct. 8, 2026

The children wanted to take Paige upstairs, isolate her, and have her speak to them with the directness and the concealed softness about the chances of their father being alive.

From "The Great Santini" by Pat Conroy

I tried to make the point, when I began the book, that the people who were involved with chatbots were social isolates.

From Slate ● Sep. 29, 2026

The team examined thousands of bacterial isolates collected from the human gut, along with large amounts of metagenomic data from people in multiple countries and across different age and health groups.

From Science Daily ● Sep. 7, 2026

Turning liquid whey into premium protein concentrates and isolates takes multimillion-dollar ultrafiltration systems and drying towers.

From The Wall Street Journal ● Jun. 20, 2026

By operating as a separate entity, GenCo isolates the cost of new growth to data centers, according to NiSource.

From Barron's ● Apr. 16, 2026

A waist-high barrier isolates it from the rest of the space.

From "The Belles" by Dhonielle Clayton

In fact, the Kremlin swiftly dismissed the idea even as the ceasefire was under way, calling Oleshky "an isolated case" which would not affect the "settlement process" – a euphemism for the stalled peace talks.

From BBC ● Nov. 2, 2026

In its lawsuit filed in a federal court in Tennessee, the FTC joined states including Alabama, Arizona and New Jersey to allege “pervasive and systemic pricing inaccuracies, rather than isolated or accidental errors.”

From The Wall Street Journal ● Oct. 31, 2026

The discoveries at Oued Beht indicate that the Maghreb was not isolated.

From Science Daily ● Oct. 31, 2026

Police said they had arrested three suspects, but the election commission described the incident as an isolated local case.

From Barron's ● Oct. 31, 2026

If the pandas are too isolated, they might be unable to find a mate or a source of food.

From "Camp Panda" by Catherine Thimmesh

MarketWatch looked at isolating just the days when oil prices rose a lot to see its effect on stocks.

From MarketWatch ● Oct. 8, 2026

For the wistful, lovelorn loner, it’s an imperative reminder that being attached at the hip can still be isolating, no matter how much two people think alike.

From Salon ● Sep. 28, 2026

For some it can be an isolating experience.

From BBC ● Aug. 15, 2026

The incidents show that the AI companies need to have stronger, industrywide standards for isolating their systems during cyber testing, said Alex Stamos, chief product officer with the cybersecurity company Corridor.

From The Wall Street Journal ● Jul. 30, 2026

I focused on isolating the data related to Castle Anorak and the forces the Sixers had positioned in and around it.

From "Ready Player One: A Novel" by Ernest Cline

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