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Synonyms

isolate

American  
[ahy-suh-leyt, ahy-suh-lit, -leyt] / ˈaɪ səˌleɪt, ˈaɪ sə lɪt, -ˌleɪt /

verb (used with object)

  • isolates,
    present (3rd person singular)
  • isolated,
    past participle,  past
  • isolating
    present participle
  1. to set or place apart; detach or separate so as to be alone.

  2. Medicine/Medical. to keep (an infected person) from contact with noninfected persons; quarantine.

  3. Chemistry, Bacteriology. to obtain (a substance or microorganism) in an uncombined or pure state.

  4. Electricity. to insulate.

  5. Television. to single out (a person, action, etc.) for a camera closeup.


noun

  1. a person, thing, or group that is set apart or isolated, as for purposes of study.

  2. Psychology. a person, often shy or lacking in social skills, who avoids the company of others and has no friends within a group.

  3. Biology. an inbreeding population that is isolated from similar populations by physiological, behavioral, or geographic barriers.

  4. Also called language isolateLinguistics. a language with no demonstrable genetic relationship, as Basque.

  5. something that has been isolated, as a by-product in a manufacturing process.

    an isolate of soy flour.

adjective

  1. isolated; alone.

isolate British  

verb

  1. to place apart; cause to be alone

  2. med to quarantine (a person or animal) having or suspected of having a contagious disease

  3. to obtain (a compound) in an uncombined form

  4. to obtain pure cultures of (bacteria, esp those causing a particular disease)

  5. electronics to prevent interaction between (circuits, components, etc); insulate

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

noun

  1. an isolated person or group

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

Derived Forms

Inflected Forms

Participles

Conjugated Forms

Present

Past

Future

Etymology

Origin of isolate

First recorded in 1800–10; back formation from isolated

Explanation

When you remove or set apart one thing from others, you isolate it. You could isolate yourself from people by living in a remote hut or, if you're a biologist, you could isolate a chromosome. The verb isolate comes from the adjective isolated, which comes from the Latin insulatas, meaning “made into an island.” You may have heard the John Donne quote, “No man is an island.” Donne was claiming that no matter how much you might try to isolate yourself from the rest of humanity, in the end people are all connected to one another. Humanity’s need for connectedness may, in fact, be illustrated by the fact that jailers frequently isolate criminals as punishment.

Keep Reading on Vocabulary.com

Vocabulary lists containing isolate

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Flowers has always been careful to isolate his family from the effects of fame.

From BBC Aug. 21, 2026

The best way to contain an outbreak is to quickly diagnose cases, isolate patients and track down all their contacts to break the chain of transmission.

From The Wall Street Journal Aug. 6, 2026

He was fined $14,650 for the protocol violation and missed a game because unvaccinated players had to isolate for 10 days after testing positive.

From Los Angeles Times Aug. 5, 2026

Spanish Prime Minister Pedro Sánchez criticized calls to isolate Spain, arguing the country’s border controls remain intact and warning against measures that could undermine European unity.

From Salon Aug. 1, 2026

The key thing about invective or ad hominem attack is that it is a sort of reverse ethos appeal: the purpose is to isolate your opponent from the community.

From "Words Like Loaded Pistols" by Sam Leith

Each successful mission further isolates Russians at the front.

From The Wall Street Journal Jun. 24, 2026

By operating as a separate entity, GenCo isolates the cost of new growth to data centers, according to NiSource.

From Barron's Apr. 16, 2026

Cars pose a direct threat to pumas of the Santa Monica Mountains, and the freeway system also isolates them from other lion populations.

From Los Angeles Times Dec. 12, 2024

The nucleolus isolates the rDNA which encodes the RNA portions of the ribosomes, the protein-building machinery.

From Science Daily Nov. 25, 2024

This is how he isolates the true impact of that single switch on the sprawling circuit board.

From "Freakonomics: A Rogue Economist Explores the Hidden Side of Everything" by Steven D. Levitt

The post-coup leadership was isolated for five years but has started a diplomatic offensive, touting deeply restricted polls it staged around the start of 2026 as a return to normality.

From Barron's Aug. 20, 2026

Losing several state AG cases would make it more difficult for Meta to say the verdicts are isolated incidents and could create significant problems for its business model.

From The Wall Street Journal Aug. 18, 2026

When everyone is writing about an outbreak of a disease, no matter how isolated, it can feel more pervasive and widespread than it actually is.

From Los Angeles Times Aug. 16, 2026

Quarks and gluons cannot remain isolated, so after the collision they quickly combine with other particles.

From Science Daily Aug. 16, 2026

Those residing in ghetto communities were particularly ill equipped to adapt to the seismic changes taking place in the U.S. economy; they were left isolated and jobless.

From "The New Jim Crow" by Michelle Alexander

For some it can be an isolating experience.

From BBC Aug. 15, 2026

The setup made it possible to recreate extreme conditions that ordinary solid materials cannot reach while isolating the effects of particle collisions.

From Science Daily Jul. 31, 2026

“Grief is really isolating, especially child loss, because very few people lose their children,” Ferrante told me, adding that her relationship with the father ended two months after Ysa’s funeral.

From Slate Jul. 19, 2026

A monthslong internet blackout has severely disrupted online commerce, further isolating the youth demographic.

From The Wall Street Journal Jun. 29, 2026

In the late 1930s, Beadle and Tatum reasoned that isolating the actual eye pigment of a fruit fly might solve the riddle of gene action.

From "The Gene" by Siddhartha Mukherjee

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