An organized visual profile of the chromosomes in the nucleus of a body cell of an organism. Karyotypes are prepared using cells in the metaphase stage of cell division, when chromosomal strands have coiled together and duplicated, rendering them easily visible under a microscope after staining. Photomicrographs of the stained chromosomes are then arranged in a standard format according to size, the relative position of the centromere, and other criteria. The normal human karyotype consists of 46 chromosomes.
To prepare the karyotype of an organism.
karyotype
Cultural
The complete set of chromosomes that constitutes the entire genome of a species. The human karyotype contains forty-six chromosomes, twenty-three from each parent. This set is contained in the nucleus of almost every cell in the body
We know this because of studies that have examined the miscarried embryos and fetuses and analyzed their DNA, or karyotype, and found that chromosomal abnormalities account for about half of all losses.