kinase

American  

[kahy-neys, -neyz, kin-eys, -eyz] / ˈkaɪ neɪs, -neɪz, ˈkɪn eɪs, -eɪz /

noun

Biochemistry.

1. a transferase that catalyzes the phosphorylation of a substrate by ATP.

---

kinase British  

/ ˈkɪn-, ˈkaɪneɪz /

noun

1. any enzyme that can convert an inactive zymogen to the corresponding enzyme

2. any enzyme that brings about the phosphorylation of a molecule

---

kinase Scientific  

/ kī′nās′,-nāz′,kĭn′ās′,-āz′ /

1. Any of various enzymes that catalyze the transfer of a phosphate group from a donor, such as ADP or ATP, to an acceptor.

---

Etymology

Origin of kinase

First recorded in 1900–05; kin(etic) + -ase

Example Sentences

By demonstrating that CENP-E regulates the earliest attachments and by connecting this regulation to Aurora kinase activity, the Zagreb team linked two processes previously thought to act separately.

From Science Daily

The protein ZAK -- a so-called kinase, that is, an enzyme which activates other molecules by transferring a phosphate group to them -- plays a central role in controlling this stress response.

From Science Daily

The researchers found that betaine binds to and blocks TBK1, a kinase that drives inflammation.

From Science Daily

PKA consists of a catalytic subunit responsible for kinase activity and a regulatory subunit that inhibits enzyme activity.

From Science Daily

Shirani's results indicate that the fact that the active catalytic subunit overrules its inhibitory components is what's important, not a structural change in the kinase itself.

From Science Daily