kinase

[kahy-neys, -neyz, kin-eys, -eyz]

noun

Biochemistry.

1. a transferase that catalyzes the phosphorylation of a substrate by ATP.

kinase

/ ˈkɪn-, ˈkaɪneɪz /

noun

1. any enzyme that can convert an inactive zymogen to the corresponding enzyme

2. any enzyme that brings about the phosphorylation of a molecule

kinase

1. Any of various enzymes that catalyze the transfer of a phosphate group from a donor, such as ADP or ATP, to an acceptor.

Word History and Origins

Origin of kinase¹

First recorded in 1900–05; kin(etic) + -ase

Word History and Origins

Origin of kinase¹

C20: from _kin ( _etic ) + _-ase

Example Sentences

The researchers found that betaine binds to and blocks TBK1, a kinase that drives inflammation.

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A protein kinase activated by cyclic adenosine monophosphate, an intracellular signaling molecule.

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Alteration in kinases, which modify many other molecules, have been implicated in driving many cancers.

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"Our group and others have used this approach before to uncover potent and selective kinase inhibitors."

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The team used a combination of laboratory experiments and computational modeling to zero in on how the molecule that serves as a sugar proxy binds to a "sensor kinase" known as KIN10.

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