lovastatin

American  

[loh-vuh-stat-n] / ˌloʊ vəˈstæt n /

noun

1. a drug, C 24 H 36 O 8 , that reduces the levels of fats in the blood by altering the enzyme activity in the liver that produces lipids.

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Etymology

Origin of lovastatin

First recorded in 1985–90; a pharmaceutical coinage

Example Sentences

A single dose of ADC therapy combined with lovastatin was found to reduce tumor volume at rates similar to those resulting from multiple doses of ADC in a preclinical setting.

From Science Daily • Oct. 13, 2023

“Similarly, grapefruit juice has a well-established interaction with both simvastatin and lovastatin that can lead to myopathy or rhabdomyolysis. Eating a grapefruit instead of drinking the juice will not avoid the interaction.”

From Washington Post • Dec. 3, 2021

Antidepressants and antihypertensives have been shown to have antiviral properties; lovastatin, which is prescribed to lower cholesterol levels, has been found to be effective, at least in mice, against plague.

From New York Times • May 12, 2020

He has already uncovered backsliders among his lovastatin patients.

From Time Magazine Archive

Researchers at Merck soon discovered similar compounds, including lovastatin, but the finds would have remained research oddities without the Nobel-prizewinning work of UTHSCD's Joseph Goldstein and Michael Brown.

From Time Magazine Archive