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Synonyms

manic-depressive

American  
[man-ik-di-pres-iv] / ˈmæn ɪk dɪˈprɛs ɪv /

adjective

  1. having or experiencing bipolar disorder.


noun

  1. a person with this disorder.

manic-depressive British  

adjective

  1. denoting a mental disorder characterized either by an alternation between extreme euphoria and deep depression (bipolar manic-depressive disorder or syndrome) or by depression on its own or (rarely) by elation on its own (unipolar disorder)

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

noun

  1. a person afflicted with this disorder Compare cyclothymia

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of manic-depressive

First recorded in 1900–05

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

“I took care of mom for 20 years before her dementia started,” she said, delving into some of the long history of their mother’s manic-depressive behavior.

From MarketWatch Jun. 30, 2026

Much has changed since Tiberius and John Law and Jefferson Davis, but not the manic-depressive nature of speculative markets.

From The Wall Street Journal Dec. 12, 2025

I know only that my mother, while still in fourth grade, watched Tomoyo go through a manic-depressive episode.

From Seattle Times May 14, 2023

Each of the manic-depressive genes discovered only increases the risk of illness by a tiny amount.

From Slate Sep. 21, 2021

Well, when it first started they said she was a manic-depressive.

From "Our America: Life and Death on the South Side of Chicago" by LeAlan Jones

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