Dictionary.com
Thesaurus.com
Synonyms

manic-depressive

American  
[man-ik-di-pres-iv] / ˈmæn ɪk dɪˈprɛs ɪv /

adjective

  1. having or experiencing bipolar disorder.


noun

  1. a person with this disorder.

manic-depressive British  

adjective

  1. denoting a mental disorder characterized either by an alternation between extreme euphoria and deep depression (bipolar manic-depressive disorder or syndrome) or by depression on its own or (rarely) by elation on its own (unipolar disorder)

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

noun

  1. a person afflicted with this disorder Compare cyclothymia

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of manic-depressive

First recorded in 1900–05

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

“This causes people to be distracted by the manic-depressive nature of the stock instead of creating great products.”

From The Wall Street Journal • Feb. 4, 2026

I know only that my mother, while still in fourth grade, watched Tomoyo go through a manic-depressive episode.

From Seattle Times • May 14, 2023

Violaine was 10 at the time of that crash; her mother, subsequently hospitalized and diagnosed as manic-depressive, was 42.

From New York Times • Oct. 19, 2021

Also important: This way he doesn’t see me cowering in the corner, ashamed of who and what I am: a manic-depressive, perimenopausal woman.

From Slate • Aug. 4, 2020

Acquaintances remember him as a socially awkward man-child with an outrageous sense of humor and a squirrelly, almost manic-depressive personality.

From "Into the Wild" by Jon Krakauer

Vocabulary.com logo
by dictionary.com

Look it up. Learn it forever.

Remember "manic-depressive" for good with VocabTrainer. Expand your vocabulary effortlessly with personalized learning tools that adapt to your goals.

Take me to Vocabulary.com