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melanoma

American  
[mel-uh-noh-muh] / ˌmɛl əˈnoʊ mə /

noun

melanomas, plural melanomata plural
  1. any of several types of skin tumors characterized by the malignant growth of melanocytes.


melanoma British  
/ ˌmɛləˈnəʊmə /

noun

  1. pathol a malignant tumour composed of melanocytes, occurring esp in the skin, often as a result of excessive exposure to sunlight

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

melanoma Scientific  
/ mĕl′ə-nōmə /
melanomas plural
  1. A dark-pigmented benign or malignant tumor that arises from a melanocyte and occurs most commonly in the skin. Malignant melanoma metastasizes quickly and is associated with sun exposure.


melanoma Cultural  
  1. A serious, often lethal, form of skin cancer.


Discover More

Exposure to ultraviolet radiation from the sun (for example, by too much sunbathing) can cause this disease.

Other Word Forms

Noun Inflected Forms

Etymology

Origin of melanoma

First recorded in 1825–35; melan- + -oma

Explanation

Melanoma is a type of skin cancer. It's important to wear sunblock and protective clothing to protect your skin and prevent melanoma. Melanoma is used for the disease itself and also an individual tumor on the skin. A melanoma often starts as a mole that grows larger or becomes irregular in shape or color. Melanoma is dangerous and fast-spreading, so it's important for people to consult a doctor if they think they have a melanoma. The medical suffix -oma, often used for tumors or growths, is added to the Greek melas, "black."

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Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

RP1 is a re-engineered herpes virus that is injected into melanoma tumors and causes cancer cells to burst.

From The Wall Street Journal Jul. 31, 2026

Replimune has said that about one-third of patients responded to the treatment, and that the median patient response stretched for nearly two years in patients whose melanoma had already progressed on standard immunotherapy.

From The Wall Street Journal Jul. 30, 2026

In 2023 he was awarded a knighthood in recognition of his campaigning work around acquired brain injury and melanoma - a type of skin cancer.

From BBC Jul. 21, 2026

Now, the same Nobel Prize winning technology is being adapted to fight cancer, with experimental mRNA vaccines already being tested against melanoma, small cell lung cancer, bladder cancer, and several other cancers.

From Science Daily Jul. 9, 2026

“Combining the melanoma cells with healthy rat skin cells to see if we can replicate the kind of alteration in the subject’s anatomy.”

From "Boy 2.0" by Tracey Baptiste

When attempting to detect skin cancers, for example, mistakes are often made by the human examiners who confuse very similar-looking but harmless conditions with potentially fatal melanomas.

From Science Daily Nov. 16, 2024

A handful of drugs known as histone deacetylase inhibitors — basically regulating the histone messaging to genes — have been developed to treat melanomas, lymphoma and other blood-borne cancers.

From Washington Post Jan. 21, 2023

Melanoma, an aggressive form of skin cancer, is highly dependent on telomerase to grow, and three-quarters of all melanomas acquire mutations in telomerase.

From Salon Nov. 24, 2022

"I had melanoma on my back, and I had a surgery to remove that as well so I am pre-composed to melanomas."

From BBC Oct. 12, 2022

He looked at human cells from breast cancers, colon cancers and melanomas and saw the same phenomenon.

From New York Times Sep. 29, 2022

He found his moles, proved that the cancers were unsuspected melanomata.

From Time Magazine Archive

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