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methylation

American  
[meth-uh-ley-shuhn] / ˌmɛθ əˈleɪ ʃən /

noun

Chemistry.
  1. the process of replacing a hydrogen atom with a methyl group.


Etymology

Origin of methylation

First recorded in 1875–80; methylate + -ion

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

"We found that disease-associated genetic variants often work by altering DNA methylation in specific immune cell types," says co-first author Wubin Ding, PhD, a postdoctoral fellow in Ecker's lab.

From Science Daily • Feb. 11, 2026

GlcHMS326 is notable for undergoing three distinct chemical modifications: glycosylation, hydroxylation, and methylation.

From Science Daily • Jan. 13, 2026

Johnson routinely measures everything from his blood sugar levels to his DNA methylation: a natural genetic change that can be used to estimate the pace of aging.

From Slate • May 28, 2025

Evaluating the merits of these awards would require a deep understanding of dozens of scientific fields, from gravitational waves to DNA methylation.

From Salon • Mar. 1, 2025

It has been explained that by the methylation of rosaniline Hofmann obtained violet colouring-matters.

From Coal and What We Get from It by Meldola, Raphael