methylglyoxal

American  

[meth-uhl-glahy-ok-sal, -suhl] / ˌmɛθ əl glaɪˈɒk sæl, -səl /

noun

Chemistry.

1. pyruvic aldehyde.

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Etymology

Origin of methylglyoxal

1895–1900; methyl- + glyoxal, equivalent to gly(col) + oxal(ic acid)

Example Sentences

They demonstrated that cells from such patients were particularly sensitive to the effects of methylglyoxal, which is a chemical produced when our cells break down glucose to create energy.

From Science Daily

The team's research also suggested that people who do not inherit a faulty copy of BRCA2 but could experience higher-than-normal levels of methylglyoxal -- such as patients with diabetes or pre-diabetes, which are connected with obesity or poor diet -- can accumulate similar warning signs indicating a higher risk of developing cancer.

From Science Daily

Prof Venkitaraman elaborated, "Our research suggests that patients with high methylglyoxal levels may have higher cancer risk. Methylglyoxal can be easily detected by a blood test for HbA1C, which could potentially be used as a marker. Furthermore, high methylglyoxal levels can usually be controlled with medicines and a good diet, creating avenues for proactive measures against the initiation of cancer."

From Science Daily

The NUS team has now found that methylglyoxal can temporarily inactivate such cancer-preventing genes, suggesting that repeated episodes of poor diet or uncontrolled diabetes can 'add up' over time to increase cancer risk.

From Science Daily

Bloch, who left a career in media to start her company, was inspired by the healing properties of manuka honey, a rare variety that contains uniquely high levels of the antibacterial compound methylglyoxal and is produced exclusively by bees that pollinate the manuka tree, a fragrant shrub that grows only in New Zealand and parts of Australia.

From New York Times