[ mon-uh-noo-klee-er, -nyoo- or, by metathesis, -kyuh-ler ]

  1. Also mon·o·nu·cle·ate. Cell Biology. having only one nucleus.

  2. Chemistry. (of hydrocarbons) monocyclic.

Origin of mononuclear

First recorded in 1885–90; mono- + nuclear

pronunciation note For mononuclear

See nuclear.

Words Nearby mononuclear Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2024

How to use mononuclear in a sentence

  • Large mononuclear leukocytes probably originate in the bone-marrow or spleen.

    A Manual of Clinical Diagnosis | James Campbell Todd
  • The remarkable character of the blood is the high percentage of large mononuclear cells.

  • In our cases the mononuclear cells have averaged 66 per cent., which is somewhat high even for infants.

    Scurvy Past and Present | Alfred Fabian Hess
  • Sharply to be distinguished from the lymphocytes is the second group: the "large mononuclear leucocytes."

    Histology of the Blood | Paul Ehrlich
  • It is especially important that the mononuclear and the leucocytes associated with them, undergo no increase.

    Histology of the Blood | Paul Ehrlich

British Dictionary definitions for mononuclear


/ (ˌmɒnəʊˈnjuːklɪə) /

  1. (of a cell) having only one nucleus

  2. another word for monocyclic (def. 1)

Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012