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mononuclear

American  
[mon-uh-noo-klee-er, -nyoo-, -kyuh-ler] / ˌmɒn əˈnu kli ər, -ˈnyu-, -kyə lər /

adjective

  1. Cell Biology. Also mononucleate. having only one nucleus.

  2. Chemistry. (of hydrocarbons) monocyclic.


mononuclear British  
/ ˌmɒnəʊˈnjuːklɪə /

adjective

  1. (of a cell) having only one nucleus

  2. another word for monocyclic

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Pronunciation

See nuclear.

Etymology

Origin of mononuclear

First recorded in 1885–90; mono- + nuclear

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

The cells, known as mononuclear phagocytes, normally circulate through the body to clear harmful substances.

From Science Daily • Oct. 23, 2025

Because the young mononuclear phagocytes did not appear to cross into the brain, researchers believe they may influence brain health indirectly.

From Science Daily • Oct. 23, 2025

"We did not see that decline in mice receiving young mononuclear phagocytes, and we believe this may be responsible for some of the memory improvements that we observed."

From Science Daily • Oct. 23, 2025

To produce youthful versions, researchers used human induced pluripotent stem cells -- adult cells reprogrammed to an early embryonic-like state -- to generate new, young mononuclear phagocytes.

From Science Daily • Oct. 23, 2025

It contains very many pseudoeosinophil cells, and indeed all stages are to be found in it, from the mononuclear cells bearing granules to the fully formed polynuclear.

From Histology of the Blood Normal and Pathological by Myers, W.

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