[mon-uh-noo-klee-er, -nyoo- or, by metathesis, -kyuh-ler]


Also mon·o·nu·cle·ate. Cell Biology. having only one nucleus.
Chemistry. (of hydrocarbons) monocyclic.

Origin of mononuclear

First recorded in 1885–90; mono- + nuclear

Pronunciation note

See nuclear. Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2019

Examples from the Web for mononuclear

Historical Examples of mononuclear

  • It is especially important that the mononuclear and the leucocytes associated with them, undergo no increase.

  • In contradistinction to the polynuclear neutrophil elements, these mononuclear forms shew no amœboid movement on the warm stage.

  • The bone-marrow forms which are free from granules consist mostly of mononuclear cells of different type.

  • The mononuclear and transitional forms of the neutrophil group, do not under normal circumstances pass over into the blood-stream.

  • We begin with the discussion of the mononuclear neutrophil cells, Ehrlich's "myelocytes."

British Dictionary definitions for mononuclear



(of a cell) having only one nucleus
another word for monocyclic (def. 1)
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Word Origin and History for mononuclear

1886; see mono- + nuclear.

Online Etymology Dictionary, © 2010 Douglas Harper

mononuclear in Medicine




Having only one nucleus.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.