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nicotinamide

American  
[nik-uh-tin-uh-mahyd, -mid, -tee-nuh-] / ˌnɪk əˈtɪn əˌmaɪd, -mɪd, -ˈti nə- /

noun

Biochemistry.
  1. a colorless, crystalline, water-soluble solid, C 6 H 6 N 2 O, the amide of nicotinic acid, and a component of the vitamin-B complex, found in meat, liver, fish, whole wheat, and eggs: used in medicine chiefly as an agent for preventing or treating human pellagra or animal black tongue.


nicotinamide British  
/ ˌnɪkəˈtɪnəˌmaɪd, -ˈtiːn- /

noun

  1. the amide of nicotinic acid: a component of the vitamin B complex and essential in the diet for the prevention of pellagra. Formula: C 6 H 6 ON 2

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of nicotinamide

First recorded in 1890–95; nicotine + amide


Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

The researchers found a 14% overall decrease in skin cancer risk among nicotinamide users.

From Science Daily ● Oct. 20, 2025

Since 2015, dermatologists have advised many patients with a history of skin cancer to consider taking nicotinamide, a form of vitamin B3.

From Science Daily ● Oct. 20, 2025

In September 2015, Diaz added two newer ones to intensify his treatment - dolutegravir and maraviroc - plus nicotinamide, a form of vitamin B3 that may help expose dormant virus.

From Washington Times ● Jul. 7, 2020

It’s also unclear how nicotinamide would awaken silent infected cells.

From Science Magazine ● Jul. 7, 2020

These electrons are in a high-energy state and are transported to NAD+, also known as nicotinamide adenine dinucleotide.

From Textbooks ● Jan. 1, 2018

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