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nicotinamide

American  
[nik-uh-tin-uh-mahyd, -mid, -tee-nuh-] / ˌnɪk əˈtɪn əˌmaɪd, -mɪd, -ˈti nə- /

noun

Biochemistry.
  1. a colorless, crystalline, water-soluble solid, C 6 H 6 N 2 O, the amide of nicotinic acid, and a component of the vitamin-B complex, found in meat, liver, fish, whole wheat, and eggs: used in medicine chiefly as an agent for preventing or treating human pellagra or animal black tongue.


nicotinamide British  
/ ˌnɪkəˈtɪnəˌmaɪd, -ˈtiːn- /

noun

  1. the amide of nicotinic acid: a component of the vitamin B complex and essential in the diet for the prevention of pellagra. Formula: C 6 H 6 ON 2

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of nicotinamide

First recorded in 1890–95; nicotine + amide

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

For CRC, key indicators included bacteria like Fusobacterium and Enterococcus, along with metabolites such as isoleucine and nicotinamide.

From Science Daily • Apr. 4, 2026

Because nicotinamide is available over the counter, its use is rarely documented in medical records.

From Science Daily • Oct. 20, 2025

In September 2015, Diaz added two newer ones to intensify his treatment - dolutegravir and maraviroc - plus nicotinamide, a form of vitamin B3 that may help expose dormant virus.

From Washington Times • Jul. 7, 2020

On top of this “intensification,” the study group received nicotinamide, which can, in theory, prod infected cells to “wake up” the latent virus.

From Science Magazine • Jul. 7, 2020

These electrons are in a high-energy state and are transported to NAD+, also known as nicotinamide adenine dinucleotide.

From Textbooks • Jan. 1, 2018

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