nicotinamide

[nik-uh-tin-uh-mahyd, -mid, -tee-nuh-]

noun

Biochemistry.

1. a colorless, crystalline, water-soluble solid, C 6 H 6 N 2 O, the amide of nicotinic acid, and a component of the vitamin-B complex, found in meat, liver, fish, whole wheat, and eggs: used in medicine chiefly as an agent for preventing or treating human pellagra or animal black tongue.

nicotinamide

/ ˌnɪkəˈtɪnəˌmaɪd, -ˈtiːn- /

noun

1. the amide of nicotinic acid: a component of the vitamin B complex and essential in the diet for the prevention of pellagra. Formula: C 6 H 6 ON 2

Word History and Origins

Origin of nicotinamide¹

First recorded in 1890–95; nicotine + amide

Example Sentences

"Even though the results are promising, we need to carry out more studies on larger populations to confirm our findings and to determine the long-term effects of nicotinamide riboside in treatment for COPD," Morten Scheibye-Knudsen explains.

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The over-the-counter supplement nicotinamide riboside, a form of vitamin B3, increased the walking endurance of patients with peripheral artery disease, a chronic leg condition for which there are few effective treatments.

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"This is a signal that nicotinamide riboside could help these patients," said Christiaan Leeuwenburgh, Ph.D., a UF professor of physiology and aging and senior author of the clinical trial report.

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The scientists recruited 90 people with an average age of 71 who had peripheral artery disease, or PAD, to test the effects of nicotinamide riboside.

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Nicotinamide riboside is a precursor for the essential compound NAD, which plays roles in the body related to energy generation, improved blood flow and DNA repair.

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