[os-uh-fi-key-shuh n]
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Origin of ossification

1690–1700; < Latin ossi-, combining form of os bone + -fication
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018

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British Dictionary definitions for ossification


  1. the formation of or conversion into bone
  2. the process of ossifying or the state of being ossified
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Word Origin and History for ossification

1690s, from Latin ossis "of bones," genitive of os "bone" (see osseous) + -fication.

Online Etymology Dictionary, © 2010 Douglas Harper

ossification in Medicine


  1. The natural process of bone formation.
  2. The hardening or calcification of soft tissue into a bonelike material.
  3. A mass or deposit of such material.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.

ossification in Science


  1. The process of bone formation, brought about by the action of specialized bone cells called osteoclasts, which absorb old bone tissue, and osteoblasts, which form from osteoclasts and produce new bone tissue. This remodeling of bone is a constant process that maintains bone strength. See more at osteoblast osteoclast.
The American Heritage® Science Dictionary Copyright © 2011. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.