Dictionary.com
Thesaurus.com
Showing results for painkiller. Search instead for painfuller.
Synonyms

painkiller

American  
[peyn-kil-er] / ˈpeɪnˌkɪl ər /

noun

  • painkillers
    plural
  1. a drug, treatment, or anything else that relieves pain, especially an analgesic.


painkiller British  
/ ˈpeɪnˌkɪlə /

noun

  1. an analgesic drug or agent

  2. anything that relieves pain

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

Derived Forms

Inflected Forms

Nouns

Etymology

Origin of painkiller

An Americanism dating back to 1850–55; pain + killer

Explanation

A painkiller is a medicine that's used to dull or relieve pain, like the painkiller your dad gives you when you have a bad headache. Painkillers are meant to do exactly what their name says: to kill pain. You can also call this kind of medication an analgesic. These range from aspirin and acetaminophen, which are sold over the counter to treat minor aches and pains, to powerful anesthetics administered by doctors before surgery. If you get your wisdom teeth removed, you'll most likely need a painkiller during and after the procedure.

Keep Reading on Vocabulary.com

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Scientific research has not identified causality between taking the painkiller and the development of those conditions in children.

From Barron's Jul. 13, 2026

Last year, Lilly acquired SiteOne Therapeutics for $1 billion, in turn assuming the rights to its experimental non-opioid painkiller, STC-004.

From Barron's Jun. 16, 2026

A decade of loyalty card data across 211 million transactions in an unnamed chain of high street stores in England found paracetamol was the most common painkiller bought alongside tampons and sanitary towels.

From BBC Jun. 14, 2026

If, say, you’ve had a stomach ulcer, the bot would recommend a painkiller that’s easy on the gut.

From The Wall Street Journal Apr. 4, 2026

“Yeah, but there’s nothing in the first aid kit that’s going to fix a tooth. I could use a painkiller, but that’s the least of our worries.”

From "Storm Runners" by Roland Smith

Low vitamin D levels may make recovery from breast cancer surgery more painful and increase the need for opioid painkillers, according to research published in Regional Anesthesia & Pain Medicine.

From Science Daily Sep. 14, 2026

Josh said the GP "found nothing wrong", prescribing more painkillers and referring him to an optician, where again no issue was found.

From BBC Jul. 28, 2026

In Pasadena, volunteers at the restaurant Chamo Venezuelan Cuisine collected supplies, issuing a special plea for bandages, gauze, painkillers and other over-the-counter medicines.

From Los Angeles Times Jun. 29, 2026

It’s clear painkillers are somewhat uncharted territory for Lilly—not a market where the company has established a presence in recent years or signaled any major plans.

From Barron's Jun. 16, 2026

There’ll be some pain but they can give you painkillers for it.”

From "Middlesex: A Novel" by Jeffrey Eugenides

Vocabulary.com logo
by dictionary.com

Join 14,000,000 vocabulary learners

Start learning new words today on VocabTrainer.
You'll remember them forever.

Start training