pathophysiology

[path-oh-fiz-ee-ol-uh-jee]

noun

Pathology.

1. the physiology of abnormal or diseased organisms or their parts; the functional changes associated with a disease or syndrome.

Word History and Origins

Origin of pathophysiology¹

First recorded in 1950–55; patho- + physiology

Example Sentences

By identifying the mechanistic role of NETs in microclot stabilization, this study provides new insight into the pathophysiology of Long COVID.

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On an almost daily basis, we learned about the shape of virus evolution, details of disease ecology, and previously unknown vagaries of human pathophysiology.

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“Unfortunately, we don’t know why. There is so much we don’t understand about the pathophysiology of what makes it more lethal for one animal than another.”

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The study, which focuses on the role of reactive astrocytes and the plexin-B1 protein in Alzheimer's pathophysiology, provides crucial insights into brain cell communication and opens the door to innovative treatment strategies.

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"This work advances understanding of schizophrenia pathophysiology at greater detail across both the complex landscape of cells within the brain, and the diverse experiences of people with this disease," said Ruzicka, who is also associate medical director of Harvard Brain Tissue Resource Center at McLean, and an assistant professor of Psychiatry at Harvard Medical School.

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