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Synonyms

pestilence

American  
[pes-tl-uhns] / ˈpɛs tl əns /

noun

  1. a deadly or virulent epidemic disease.

  2. bubonic plague.

  3. something that is considered harmful, destructive, or evil.


pestilence British  
/ ˈpɛstɪləns /

noun

    1. any epidemic outbreak of a deadly and highly infectious disease, such as the plague

    2. such a disease

  1. an evil influence or idea

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

Etymology

Origin of pestilence

First recorded in 1275–1325; Middle English, from Middle French, from Latin pestilentia, from pestilent-, stem of pestilēns “unhealthy, noxious” ( see pestilent) + -ia -y 3 ( def. )

Explanation

Pestilence means a deadly and overwhelming disease that affects an entire community. The Black Plague, a disease that killed over thirty percent of Europe's population, was certainly a pestilence. Pestilence is also one of the Four Horsemen of the Apocalypse in the Book of Revelation (which is part of The Bible). When pestilence rides into town, you want to be somewhere far, far away. Whereas a person gets the flu, a nation experiences a pestilence. A disease that causes widespread crop damage or animal deaths can also be called a pestilence.

Keep Reading on Vocabulary.com

Vocabulary lists containing pestilence

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

When will we be rid of this pestilence?

From Slate Jul. 17, 2026

Without them, we’d live in a world of putridity and pestilence.

From The Wall Street Journal Apr. 30, 2026

Every time she opens her mouth I swear a swarm of horseflies and pestilence are released to consume the countryside.

From Salon Nov. 28, 2025

There’s anguish in his eyes, and when Del Toro shows us the world through his perspective, humanity itself appears anti-life, a pestilence that destroys without hesitation.

From Los Angeles Times Oct. 16, 2025

He threw out a wave of pestilence and decay.

From "City of the Plague God" by Sarwat Chadda

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