[fahy-soh-stig-meen, -min]

noun Pharmacology.

an alkaloid, C15H21N3O2, used in the treatment of Alzheimer's disease to raise the level of the neurotransmitter acetylcholine and also as a miotic in glaucoma.

Origin of physostigmine

1860–65; < New Latin Physostigm(a) genus of plants yielding the alkaloid (see physo-, stigma) + -ine2 Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2019

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Historical Examples of physostigmine

British Dictionary definitions for physostigmine


physostigmin (ˌfaɪsəʊˈstɪɡmɪn)


an alkaloid found in the Calabar bean used esp in eye drops to reduce pressure inside the eyeball. Formula: C 15 H 21 N 3 O 2Also called: eserine

Word Origin for physostigmine

C19: from New Latin Physostigma genus name, from Greek phusa bladder + stigma mark
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012