- an alkaloid, C15H21N3O2, used in the treatment of Alzheimer's disease to raise the level of the neurotransmitter acetylcholine and also as a miotic in glaucoma.
Origin of physostigmine
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018
Examples from the Web for physostigmine
After subcutaneous or local application, a dilatation neutralised by physostigmine in moderate doses.
Physostigmine contracts the iris to a point; the action is quite local, and is confined to the eye to which it is applied.
Each of these contains one-thousandth part of a grain of physostigmine sulphate, a quantity which is perfectly efficient.
The respiration is at first accelerated by a dose of physostigmine, but is afterwards slowed and ultimately arrested.
There is a marked antagonism in nearly all important particulars between the actions of physostigmine and of atropine.
- an alkaloid found in the Calabar bean used esp in eye drops to reduce pressure inside the eyeball. Formula: C 15 H 21 N 3 O 2Also called: eserine
C19: from New Latin Physostigma genus name, from Greek phusa bladder + stigma mark