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Origin of prion1
Words nearby prion
Definition for prion (2 of 2)
Example sentences from the Web for prion
Onset is typically during middle age, which is characteristic of the long incubation periods most prion diseases show.Necrotizing Fasciitis, Blinding Larvae & More Scary Diseases|Casey Schwartz|May 18, 2012|DAILY BEAST
Caused by a deformed protein known as a prion, the disease attacks and destroys the brain and spinal cord in cattle.
Even now the farms at the back of the Prion retain the name in the term Opistholepria.
Prion lui donc merci seurement se diable nus uout enconbrer .
British Dictionary definitions for prion (1 of 2)
Word Origin for prion
British Dictionary definitions for prion (2 of 2)
Word Origin for prion
Medical definitions for prion
Scientific definitions for prion
A Closer Look
In 1997 Stanley Prusiner was awarded the Nobel Prize for physiology or medicine for his theory that a deviant form of a harmless protein could be an infectious agent, a transmitter of disease. Named prions (short for proteinaceous infectious particle), these misshapen proteins cause healthy proteins to misfold, fatally clumping together in the brain. Unlike other disease-causing agents, prions lack genetic material (DNA and RNA). Neurodegenerative prion diseases are often called spongiform encephalopathies because they leave the brain riddled with holes like a sponge. In animals, prion diseases include scrapie in sheep and bovine spongiform encephalopathy, commonly known as mad cow disease in cattle. In humans, diseases such as kuru and Creutzfeldt-Jakob disease (CJD) are also thought to be caused by prions. All the diseases are characterized by loss of motor control, dementia, paralysis, and eventual death due to massive destruction of brain tissue. Humans are thought to contract prion disease most commonly by eating prion-contaminated flesh. Kuru, a rare and fatal brain disorder, brought prion disease to the forefront. First described in the 1950s, kuru was most common among the Fore people of Papua New Guinea, who had a custom of eating the brains of their dead during funeral feasts. It is speculated that a tribe member developed CJD, his or her contaminated brain tissue was ingested, and the disease spread. Kuru reached epidemic levels in the 1960s, but the disease declined after the government discouraged the practice of cannibalism and now it has almost completely disappeared.
Cultural definitions for prion
A protein that not only folds into an unusual shape itself, but also seems to have the ability to cause other proteins to change their shape as well. For a long time, scientists were skeptical that prions existed, but now most accept them.