proband

[ proh-band ]
/ ˈproʊ bænd /

noun Genetics.

a patient who is the initial member of a family to come under study.

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What does “barren” mean?
Also called propositus.

Origin of proband

1925–30; <Latin probandus, gerundive of probāre to test, probe
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2020

British Dictionary definitions for proband

proband
/ (ˈprəʊbænd) /

noun

another name (esp US) for propositus (def. 2)

Word Origin for proband

C20: from Latin probandus, gerundive of probāre to test
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Medical definitions for proband

proband
[ prōbănd′ ]

n.

An individual or member of a family being studied in a genetic investigation.index case propositus
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.