[ proh-band ]
/ ˈproʊ bænd /

noun Genetics.

a patient who is the initial member of a family to come under study.

Origin of proband

1925–30; < Latin probandus, gerundive of probāre to test, probe
Also called propositus. Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2019

British Dictionary definitions for proband


/ (ˈprəʊbænd) /


another name (esp US) for propositus (def. 2)

Word Origin for proband

C20: from Latin probandus, gerundive of probāre to test
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Word Origin and History for proband



1929, from Latin probandus, gerundive of probare "to make good, esteem good; make credible, show, prove, demonstrate" (see prove).

Online Etymology Dictionary, © 2010 Douglas Harper

Medicine definitions for proband


[ prōbănd′ ]


An individual or member of a family being studied in a genetic investigation.index case propositus
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.