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proband

American  
[proh-band] / ˈproʊ bænd /

noun

Genetics.
  1. a patient who is the initial member of a family to come under study.


proband British  
/ ˈprəʊbænd /

noun

  1. another name (esp US) for propositus

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of proband

1925–30; < Latin probandus, gerundive of probāre to test, probe